“…The United Stated of America National Inpatient Sample from 1998 to 2013 reported the occurrence of air embolism in 3.32 per 100,000 ERCP procedures [ 5 ]. With only 60 cases of air embolism reported (and even fewer related to paradoxical air embolism) [ 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ], we aimed to report a case of paradoxical cerebral air embolism in a patient undergoing ERCP due to a common bile duct (CBD) stricture and to provide a mini-review of this clinical entity that can serve as a bedside quick reference guide for endoscopists worldwide.…”