Embolic stroke from cardiac papillary fibroelastomas.

Kasarskis, E. J.; O’Connor, William N.; Earle, Gary F.

doi:10.1161/01.str.19.9.1171

Cited by 73 publications

(27 citation statements)

References 6 publications

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“…Their role in myocardial infarct and sudden death was then suspected and broadly reported in the cardiovascular literature [20]. We found 21 cases [3, 7, 8, 12, 13, 15, 17, 19, 21, 22, 23, 24, 25, 26], 10 males and 11 females, including ours, of patients clinically documented enough with a pathological demonstration of a papillary fibroelastoma discovered after a neurological event: transient ischemic attack (TIA), stroke or retinal ischemia (table 1). The patients were generally asymptomatic without any cardiac signs.…”

Section: Discussionmentioning

confidence: 95%

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Cardiac Papillary Fibroelastoma:A Rare Cause of Isch emic Stroke in the Young

Giannesini¹,

Kubis²,

Nguyen³

et al. 1999

Cerebrovasc Dis

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Among etiologies of stroke in young adults, primary cardiac tumors are very rare. We report the case of a 37-year-old woman who was admitted for an ischemic stroke in the right middle cerebral artery region. Etiologic investigations revealed, after transthoracic and transesophageal echocardiography, an aortic valve tumor. Treatment was first medical with anticoagulation, then surgical. Histological examination showed a papillary fibroelastoma. After a review of the literature, the possible mechanisms of the ischemic event are discussed and lead to the conclusion that this tumor must be surgically excised, even if asymptomatic, because of recurrent ischemic complications responsible for myocardial infarction, stroke and sudden death.

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Section: Discussionmentioning

confidence: 95%

“…Their predominant location is the noncontact surfaces of the aortic valve [4, 6], like in our case. The size of this tumor discovered after a neurological ischemic event has been reported to range from 4 [7]to 18 mm [8]. This is of course highly dependent on the mean of detection of the tumor.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Papillary Fibroelastoma:A Rare Cause of Isch emic Stroke in the Young

Giannesini¹,

Kubis²,

Nguyen³

et al. 1999

Cerebrovasc Dis

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“…Most lesions are less than 1 cm in diameter, but these tumors range in size from 0.1-4 cm. 13,14) The size of the tumors reported by MDCT is around 9-10 mm. [7][8][9] Valvular CPF arises almost exclusively in the mid-portion of the valve, without encroaching on the annulus or the free edge of the valve leaflet.…”

Section: Discussionmentioning

confidence: 99%

Papillary Fibroelastoma of the Aortic Valve Visualized by 320-slice Computed Tomography: Report of a Case

Kin

Koizumi

Yoshioka

et al. 2011

ATCS

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A 72-year-old man presented with a papillary fibroelastoma on the non-coronary cusp of the aortic valve. He was asymptomatic, with a history of hypertension and paroxysmal atrial fibrillation. Echocardiography revealed a mobile, round mass (13 × 15 mm) on the non-coronary cusp of the aortic valve. Scanning with 320-slice multi-detector row computed tomography (MDCT) also revealed a mass on the non-coronary cusp of the aortic valve. The tumor was subsequently excised from the aortic valve. In this case, the MDCT images were extremely clear and provided useful information like that obtained with echocardiography.

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“…Approximately 100 years later, these structures were further histopathologically differentiated by F. Margarey [16]. At present, it is unclear if Lambl’s excrescences are macroscopically or histologically distinguishable from cardiac papillary fibroelastomas, hamartomas and other benign cardiac tumors [17, 18]. While there does not seem to be a consensus in the literature on the correct terminology and nomenclature of these structures [19], some authors argue that cardiac papillary fibroelastoma may apply to a subset of Lambl’s and Margarey’s initial findings [20].…”

Section: Discussionmentioning

confidence: 99%

Valvular Strands and Ischemic Stroke

Spiess

Vasić²,

Huber

2007

Eur Neurol

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We report the case of a previously healthy 47-year-old woman suffering an acute embolic stroke in the left middle cerebral artery distribution. A filiform structure along the line of the aortic valve was first identified by transesophageal echocardiography, leading to the diagnosis of a valvular strand. These masses are thought to represent giant Lambl’s excrescences, although differential diagnoses include several benign cardiac tumors, e.g. papillary fibroelastoma. Valvular strands have previously been associated with embolic events including stroke, although exact pathogenetic mechanisms and further patient management have not yet been fully established. This case report additionally provides a short overview of the currently existing literature. As a conclusion, standard recommendations for patient management and treatment cannot be derived from currently available evidence.

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Embolic stroke from cardiac papillary fibroelastomas.

Cited by 73 publications

References 6 publications

Cardiac Papillary Fibroelastoma:A Rare Cause of Isch emic Stroke in the Young

Cardiac Papillary Fibroelastoma:A Rare Cause of Isch emic Stroke in the Young

Papillary Fibroelastoma of the Aortic Valve Visualized by 320-slice Computed Tomography: Report of a Case

Valvular Strands and Ischemic Stroke

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