Embolic atrial myxoma with neoplastic aneurysm formation and haemorrhage: a diagnostic challenge

Rodriguez, F. J.; Brown, Robert D.; Mohr, J. P.; Piepgras, David G.; Thielen, Kent R.; Blume, R; Connolly, Heidi M.; Petty, George W.; Giannini, Caterina

doi:10.1111/j.1365-2990.2006.00721.x

Cited by 24 publications

(21 citation statements)

References 18 publications

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“…The pathology of neurological manifestation secondary to left atrial myxoma is threefold: cerebral arterial embolism causing cerebral infarctions, aneurysms and intraparenchymal metastases [7][8][9]. Since the first reported description of a stroke caused by a cardiac myxoma in 1952 [10], there have been a handful of published case reports and series describing atrial myxoma and secondary cerebral infarctions.…”

Section: Introductionmentioning

confidence: 99%

The imaging features of neurologic complications of left atrial myxomas

Liao

Ramkalawan

Liu

et al. 2015

European Journal of Radiology

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Section: Introductionmentioning

confidence: 99%

The imaging features of neurologic complications of left atrial myxomas

Liao

Ramkalawan

Liu

et al. 2015

European Journal of Radiology

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“…Cardiac myxomas are usually attached by a stalk to the atrial septum in the fossa ovalis, and their range of movement is dependent on stalk length, tumour size, and morpho logy. Cardiac myxomas will enhance with use of echocardiography contrast 13,[17][18][19][20] . Differential diagnosis at imaging includes other tumour types, such as papillary fibroelastomas, blood cysts, sarcomas, fibromas, rhabdo myomas, thrombi, and metastases.…”

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confidence: 98%

Pathology, imaging, and treatment of cardiac tumours

et al. 2017

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Cardiac tumours are a rare, but often devastating, clinical diagnosis. They encompass a broad set of lesions that include both neoplastic and non-neoplastic conditions. Cardiac tumours are often diagnosed incidentally during work-up for other conditions, or during ultrasound, CT, or MRI scans for unusual or nonspecific symptoms. In the past decade, important changes have been made in the nomenclature and the recommendations for diagnosis of cardiac tumours, as highlighted by the WHO's 2015 revision of the classification of cardiac tumours. Moreover, important advances in molecular genetics and therapeutics offer new approaches for the diagnosis and treatment of affected patients. In this Review, we provide an overview of the clinical, pathological, and imaging characteristics of all types of cardiac masses, including both benign and malignant primary cardiac neoplasms.

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“…9,12,[14][15][16] Furthermore, although the authors of a case series have shown that the immediate central nervous system manifestations are often severe and may be fatal, the manifestations also indicated a good prognosis with respect to the recurrence of neurological events. 11,[14][15][16] In contrast, spontaneous regression or stabilization has been demonstrated in patients in whom the primary atrial tumor was removed. 1 Branch et al 4 have reported cases of an angiographically proven resolution of a fusiform cerebral aneurysm after removal of a cardiac tumor.…”

Section: Discussionmentioning

confidence: 99%

Multiple fusiform myxomatous cerebral aneurysms in a patient with Carney complex

Ryou

Lee²,

Park³

et al. 2008

JNS

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Carney complex is a rare autosomal-dominant familial tumor syndrome that involves the triad of myxoma, mucocutaneous pigmentation, and endocrine overactivity. To the best of the authors' knowledge, there are no reports of multiple fusiform aneurysms coinciding with atrial myxoma. The authors report the case of a 38-year-old woman with typical Carney complex who had multiple skin myxomas, endocrine abnormalities, and multiple brownish perioral lesions. Multiple fusiform aneurysms were also discovered after the recurrence of atrial myxoma. During a follow-up period of > 10 years, there have been no angiographic changes in the aneurysms and no progression of symptoms.

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Embolic atrial myxoma with neoplastic aneurysm formation and haemorrhage: a diagnostic challenge

Cited by 24 publications

References 18 publications

The imaging features of neurologic complications of left atrial myxomas

The imaging features of neurologic complications of left atrial myxomas

Pathology, imaging, and treatment of cardiac tumours

Multiple fusiform myxomatous cerebral aneurysms in a patient with Carney complex

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