Embolia pulmonar aguda durante la cuarentena por COVID-19

Vannini, Luca; Gómez, Joaquín Marchena; Quijada-Fumero, Alejandro; Pérez, Ana Belén Fernández; Hernández-Afonso, Julio

doi:10.1016/j.recesp.2020.05.015

Cited by 6 publications

(5 citation statements)

References 4 publications

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“…Este hallazgo no parece tener relación con la presencia de infección por el virus SARS-CoV-2, pues ningún paciente con enfermedad tromboembólica había sido diagnosticado de dicha infección, además el área geográfica en la que se llevó a cabo el estudio no presentaba una elevada incidencia de casos durante las primeras semanas de pandemia 20 en salud relacionados con la actividad física sí puede estar implicado en esta relación entre confinamiento y tromboembolismo. Estudios previos han analizado esta posible relación, observando su existencia, aunque se trata de pocos casos y no se identificó el tiempo necesario de reposo sin hacer actividad para producir enfermedad tromboembólica 23 . Otro estudio de casos y controles, hecho en 2013, observó una asociación débil entre el tromboembolismo venoso y la inmovilidad prolongada relacionada con el trabajo y el uso del ordenador, con un aumento promedio de horas sentado asociado a un mayor riesgo de tromboembolismo venoso 24 .…”

Section: Discussionunclassified

Impacto del confinamiento durante la pandemia de COVID-19 en la prevalencia de la enfermedad tromboembólica venosa

Carbajo Martín,

Domínguez Rite,

Martín Brioso

et al. 2024

Rev Clín Med Fam

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Objetivo: comparar la frecuencia de eventos tromboembólicos agudos en pacientes atendidos en urgencias de un hospital comarcal durante las primeras semanas de la pandemia de COVID-19 del año 2020 respecto al año anterior. Material y métodos: estudio retrospectivo en pacientes mayores de 40 años atendidos en urgencias del Hospital de Riotinto (Huelva) desde el 15 de marzo al 30 de abril de los años 2019 y 2020. La recogida de información se llevó a cabo a partir de una revisión de historias clínicas y el cuestionario de recogida de datos contenía variables clínicas y sociodemográficas. Resultados: se incluyeron 1.245 pacientes. Edad media: 71,2 años (desviación estándar [DE]: 13,7) y un 51,1% eran mujeres. En 2019 se atendieron a 797 mayores de 40 años y en 2020 fueron 448, suponiendo un descenso del 43,79%. La prevalencia de embolismo pulmonar fue superior en 2020 respecto a 2019 (1,6% frente a 0,4%; p = 0,024). La frecuencia de eventos trombóticos venosos fue superior también en 2020 respecto a 2019 (1,35% frente a 0,4%; p = 0,054). La prevalencia global de la enfermedad tromboembólica venosa con variable compuesta (tromboembolismo pulmonar + trombosis venosa) fue significativamente superior en 2020 frente a 2019 (2,9% frente a 0,8%; p = 0,003). Ningún paciente fue diagnosticado de COVID-19 y tromboembolismo. Conclusiones: en el período de confinamiento durante la pandemia hubo un incremento del número de eventos tromboembólicos agudos en adultos, tanto de tromboembolia pulmonar como de trombosis venosa profunda respecto al año previo. Palabras clave: SARS-CoV-2, pandemia, tromboembolia venosa, embolia pulmonar.

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Section: Discussionunclassified

Impacto del confinamiento durante la pandemia de COVID-19 en la prevalencia de la enfermedad tromboembólica venosa

Carbajo Martín,

Domínguez Rite,

Martín Brioso

et al. 2024

Rev Clín Med Fam

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“…With regard to hypercoagulability or thrombophilia (second element of Virchow's triad), thrombophilia can be genetic or acquired. In the rst place, Factor V Leiden has been described as a genetic factor; the G20210A prothrombin gene mutation in second place; and the mutation of the enzyme methylene-tetrahydro-folate-reductase in third place [5,6]. Anti-phospholipid syndrome, systemic lupus erythematosus, resistance to protein C, hyperhomocystinemia, sticky platelet syndrome, and cancer have been described as acquired factors [6].…”

Section: Discussionmentioning

confidence: 99%

Immobility due to COVID-19 confinement, use of contraceptives and presence of the G20210A mutation. Validity of the Virchow triad for the presentation of Deep Venous Thrombosis and Pulmonary Thromboembolism.

Casique-Bocanegra

Rodríguez-Garrote

Danabayeva

et al. 2021

Preprint

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Venous thromboembolic disease is a complex and multifactorial pathology, the result of the interaction of both genetic and environmental factors. The Virchow triad, first described in 1859, is still valid to explain the pathogenesis of thrombosis, where three main factors are reflected: a) hypercoagulable state; b) impaired blood flow; c) endothelial injury. The outbreak of a new COVID-19 pandemic has led to drastic confinement measures, with the consequent syndrome of immobility, as occurred in Spain between the months of March to June 2020. Pregnancy and hormonal contraception have proven to be an environmental factor predisposing to venous thrombosis. The presence of genetic factors, such as the mutation of the prothrombin gene G20210A, has been shown to be a risk factor for the presentation of venous thrombosis. We present the case of a 23-year-old non-smoking woman, a heterozygous carrier of a prothrombin gene mutation G20210A (hypercoagulability), who after confinement due to COVID-19 (impaired blood flow due to immobility) and use of hormonal patch contraceptives (endothelial abnormality), triggered deep vein thrombosis (DVT) / pulmonary thromboembolism (PE) that required hospital admission; and who, after rapid withdrawal of anticoagulant treatment, presented a second and a third episode of DVT. We highlight the usefulness of evaluating risk factors in G20210A heterozygous patients and the proper management of anticoagulation to avoid recurrences in patients susceptible to DVT / PE.

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“…9,10 Similarly, in another study, pulmonary complications were more common in all elderly patients with COVID-19 during the pandemic. 11 This retrospective study examines the outcomes of geriatric patients with extracapsular fractures during the COVID-19 pandemic. The obtained data was compared with patient outcomes from a nonpandemic period.…”

Section: Anah Tar Ke LI Me Ler: Kalça Kırıkları; Covid-19;mentioning

confidence: 99%

Retrospective Analysis of Extracapsular Hip Fracture Outcomes Before and During the Pandemic: A Comparative Cohort Study

GEZER,

ÇAKIR TURHAN,

BAYTAŞ

et al. 2024

Turkiye Klinikleri J Anest Reanim

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In response, measures were quickly implemented that completely transformed the healthcare system and daily life. As a result of these changes, the priorities for hospitalization and treatment plans have shifted. This study aims to retrospectively evaluate and compare the outcomes of geriatric patients who underwent surgery for anextracapsular hip fracture during the one year pre-pandemic and pandemic periods. Material and Methods: Only those who underwent surgery for extracapsular hip fracture were included in the study to ensure surgical standardization. We obtained patient data from the hospital's digital archive and assessed demographic characteristics, location of the trauma, anesthesia method, postoperative outcomes, length of hospital stay, and intensive care requirements. Results: 191 patients underwent surgery for an extracapsular hip fracture indication during the specified time intervals. Out of these, 71 (were male and 120 were female. Among the patients, 117 were in Group 1 (surgery before the pandemic) and 74 were in Group 2 (surgery during the pandemic). Although Group 2 had a larger number of patients with American Society of Anesthesiologists III and diabetes, there were no significant differences between the two groups in terms of postoperative complications and mortality. Group 2 patients were more likely to have sustained trauma outdoors. Conclusion: The study highlights how the pandemic has affected the lives of both patients and healthcare professionals and how it continues to do so.

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Embolia pulmonar aguda durante la cuarentena por COVID-19

Cited by 6 publications

References 4 publications

Impacto del confinamiento durante la pandemia de COVID-19 en la prevalencia de la enfermedad tromboembólica venosa

Impacto del confinamiento durante la pandemia de COVID-19 en la prevalencia de la enfermedad tromboembólica venosa

Immobility due to COVID-19 confinement, use of contraceptives and presence of the G20210A mutation. Validity of the Virchow triad for the presentation of Deep Venous Thrombosis and Pulmonary Thromboembolism.

Retrospective Analysis of Extracapsular Hip Fracture Outcomes Before and During the Pandemic: A Comparative Cohort Study

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