EMAS position statement: Diet and health in midlife and beyond

Lambrinoudaki, Ιrene; Ceasu, Iuliana; Depypere, Herman; Erel, C. Tamer; Rees, Margaret; Schenck‐Gustafsson, Karin; Simoncini, Tommaso; Trémollières, Florence; Schouw, Yvonne T. van der; Pérez‐López, Faustino R.

doi:10.1016/j.maturitas.2012.10.019

Cited by 38 publications

(19 citation statements)

References 89 publications

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“…Epidemiological research has been conducted in the past two decades to address the status and effects of fruit and vegetable intake in several populations. As expected (Hippocrates, V century BC), high daily intake of fruits and vegetables is integrative part of a healthy lifestyle (Lambrinoudaki et al 2013). Interestingly, the term ''diaeta'' was adopted by the Romans from the word ''dia 9 g 9 sa''-with which the ancient Greeks intended the ''way of living,'' not only nutrition.…”

Section: Why Should We Care About Diet and Nutrition Against Cognitivsupporting

confidence: 54%

Nutritional contributions to dementia prevention: main issues on antioxidant micronutrients

Polidori

Schulz

2014

Genes Nutr

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There is an impressing body of evidence supporting the beneficial role of balanced nutrition in lowering the risk of dementia and its commonest form, Alzheimer's disease. Nevertheless, and despite worldwide dementia epidemic, there is much unfounded skepticism and lack of information among physicians. As a result, the diagnosis of cognitive impairment occurs still far too late, at best symptomatic drugs keep being prescribed and patients and caregivers are left with little concrete support in the hands of the natural history of the disease. This review summarizes knowledge about the impact of nutrition as part of a healthy lifestyle and of micronutrients in particular on delaying and avoiding dementia onset.Why do we need to care about dementia Dementia is the most prevalent neurodegenerative disorder, and it is characterized by progression, multiple etiology, complex symptomatology including that related to a disturbance of cognitive performance and absence of a cure. During the course of the disease, the cognitive symptoms of dementia persist and steadily worsen and behavioral disturbances appear and progress and as a result intellectual and social abilities are affected enough to obstacle the performance of activities of daily living. According to dementia definition, a diagnosis of dementia can be done when the impairment of more cognitive domains lasts long enough and is associated with behavioral disturbances both affecting activities of daily living. Dementia is indeed associated with disability and a high grade of dependence on caregivers-usually family members. This condition of disability and dependence brings along an enormous social and economic burden which is linked to the epidemics of dementia and its commonest, untreatable form, Alzheimer's disease (AD). The major risk factor for dementia and AD is advanced age, and therefore, the societal impact of AD is increasing according to aging demographics (http:// ec.europa.eu/health/reports/european). Life expectancy at birth in the EU increased from 72 years in 1980 to 78 years in 2007. The population of industrialized countries progressed from a mean life expectancy of 35 years at the beginning of the last century, to currently over 80 years of age. People aged 65 years or older are expected to double between 1995 and 2050 to reach 135 million in the EU, with very old people, aged 80 years and older, being projected to grow as much as eight to ten times on the global scale by 2050. This will strongly impact the already challenging number of ten million AD cases in the EU. As a cure against dementia has not been found yet, health care professionals all over the world are predicted to face the diagnostic, therapeutic and socioeconomical challenges of over 115 million people with dementia by 2050 (Prince et al. 2013). This perspective might be even underestimated, particularly due to inadequate diagnosis, lack of awareness and low education. The dramatic loss of synapses and cholinergic neurons, accumulation of extracellular b amyloid (Ab) plaqu...

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Section: Why Should We Care About Diet and Nutrition Against Cognitivsupporting

confidence: 54%

Nutritional contributions to dementia prevention: main issues on antioxidant micronutrients

Polidori

Schulz

2014

Genes Nutr

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“…Whereas weight gain per se cannot be attributed to the menopause transition, the change in the hormonal milieu at menopause is associated with an increase in total body fat and an increase in abdominal fat [11]. Thus women should be encouraged to stop smoking, to have a balanced healthy diet rich in fibre, fruit and vegetables and to exercise regularly, aiming to prevent the midlife increase in body weight and to preserve their muscle mass [12,13]. With regard to hot flushes a Cochrane review concluded that 'evidence was insufficient to show whether exercise is an effective treatment for vasomotor menopausal symptoms' [14].…”

Section: Diet and Lifestylementioning

confidence: 99%

EMAS position statement: The ten point guide to the integral management of menopausal health

et al. 2015

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“…Consumption of nuts and seeds, appropriate intake of calcium and vitamin D, and low intakes of alcohol and sodium are additional crucial dietary changes. The recommended calcium and vitamin D daily intakes for women older than 50 years with a risk of fracture are 1000-1200 mg and 600-800 IU, respectively [58][59][60][61][62].…”

Section: Management Of T2dm In Women During and After Menopausementioning

confidence: 99%

Menopause and diabetes: EMAS clinical guide

et al. 2018

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Introduction: Whether menopause increases the risk of type 2 diabetes mellitus (T2DM) independently of ageing has been a matter of debate. Controversy also exists about the benefits and risks of menopausal hormone therapy (MHT) in women with T2DM. Aims: To summarise the evidence on 1) the effect of menopause on metabolic parameters and the risk of T2DM, 2) the effect of T2DM on age at menopause, 3) the effect of MHT on the risk of T2DM, and 4) the management of postmenopausal women with T2DM. Materials and methods: Literature review and consensus of experts' opinions. Results and conclusion: Metabolic changes during the menopausal transition include an increase in and the central redistribution of adipose tissue, as well as a decrease in energy expenditure. In addition, there is impairment of insulin secretion and insulin sensitivity and an increase in the risk of T2DM. MHT has a favourable effect on glucose metabolism, both in women with and in women without T2DM, while it may delay the onset of T2DM. MHT in women with T2DM should be administered according to their risk of cardiovascular disease (CVD). In women with T2DM and low CVD risk, oral oestrogens may be preferred, while transdermal 17βoestradiol is preferred for women with T2DM and coexistent CVD risk factors, such as obesity. In any case, a progestogen with neutral effects on glucose metabolism should be used, such as progesterone, dydrogesterone or transdermal norethisterone. Postmenopausal women with T2DM should be managed primarily with lifestyle intervention, including diet and exercise. Most of them will eventually require pharmacological therapy. The

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EMAS position statement: Diet and health in midlife and beyond

Cited by 38 publications

References 89 publications

Nutritional contributions to dementia prevention: main issues on antioxidant micronutrients

Nutritional contributions to dementia prevention: main issues on antioxidant micronutrients

EMAS position statement: The ten point guide to the integral management of menopausal health

Menopause and diabetes: EMAS clinical guide

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