Bifidobacterium breve alleviates gut–liver-axis injury caused by high-fat diet and aflatoxin B1 in mice
Yongli Ye,
Tingwei Wang,
Jian Ji
et al.
Abstract:Aflatoxin B 1 (AFB1) is a common contaminant in cereals of global concern, and long-term low-dose exposure can adversely affect human health. Here, we showed that populations with dietary patterns characterized by high-fat diet (HFD) might have an increased risk of exposure to high levels of AFB1. Our data indicated that chronic exposure of AFB1 induced "gut-liver axis" injury in mice under HFD and normal diet (ND) patterns. AFB1 further aggravated hepatic and intestinal injury, and intestinal microbiota disru… Show more
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