Elucidation of Interactions between l‐Ascorbic Acid and Mixed Micellar Aggregates of Catanionic {Sodium Dodecylsulfate + Cetyltrimethylammonium Bromide} Surfactants via Physicochemical and Spectroscopic Studies

Abstract

Surfactant micelles mimic the microenvironment present in biological systems and can act as a medium for antioxidant studies. Moreover, the thermodynamic profile of micellization and spectroscopic studies provides very good information about interactions in these systems. Thus, the mixed micellar behavior of sodium dodecylsulfate (SDS) and cetyltrimethylammonium bromide (CTAB) at varying mole fractions of SDS was studied in (0.01, 0.02, and 0.03) mol kg−1 ʟ‐ascorbic acid(aq) solutions with the aid of various techniques viz., conductivity, density and sound velocity, and spectroscopy. From the CMC values of the mixed surfactants, the degree of ionization (β) and thermodynamic parameters (normalΔGm°, normalΔHm°, and normalΔSm°) were evaluated at 298.15, 308.15, and 318.15 K. The UV absorption spectra were recorded in (1–3) × 10−4 mol kg−1 ʟ‐ascorbic acid(aq) solutions at various mole fractions of SDS. The proton (1H) NMR spectra of mixed (SDS + CTAB) surfactants were studied in (0.01–0.03) mol kg−1 ʟ‐ascorbic acid solutions. Hydrodynamic diameters (Dh) of mixed micellar aggregates were obtained from the dynamic light scattering (DLS) studies. The present studies suggest the predominance of ionic‐hydrophilic interactions between the ionic head groups {O‐SO3− or N+ (CH3)3} of surfactants and the polar (–OH, –C=O and –O–) sites of ʟ‐ascorbic acid.

Non-centrosymmetric Hollow BiOCl Nanocaps with Tailored Openings for the Photocatalytic Degradation of Rhodamine B

“…As reported in the literature, ionic–hydrophilic interactions between the ionic head groups −N + (CH 3 ) 3 of surfactants and the polar sites (−OH, −CO and −O−) of l -ascorbic acid make l -ascorbic acid interacts strongly with the micellar system. Thus, when added into the CTAC solution, l -ascorbic acid distributes around the surface of CTAC micelles. − The DLS measurement confirms that the size of micelles is slightly increased after adding l -ascorbic acid (Figure S7a). With the addition of Bi 3+ precursor solution, Bi 3+ may form metastable complex intermediates with l -ascorbic acid due to the coordination ability of l -ascorbic acid, and similar complexes have been reported .…”

“…39−42 The DLS measurement confirms that the size of micelles is slightly increased after adding L-ascorbic acid (Figure S7a). 41 With the addition of Bi 3+ precursor solution, Bi 3+ may form metastable complex intermediates with L-ascorbic acid due to the coordination ability of L-ascorbic acid, and similar complexes have been reported. 43 Therefore, the release rate of Bi 3+ from the metastable complexes can be readily manipulated by the concentration of L-ascorbic acid.…”

Mixed Micellization Behavior of (Chlorpromazine Hydrochloride + Cetyltrimethylammonium Bromide) System in Aqueous Solutions of Glycine

“…The literature survey reflects extensive studies of conventional surfactants in aqueous additive solutions (Banipal et al, 2010; Domanska et al, 2009; Iqbal and Chaudhry, 2009; Martinez and Gomez, 2002; Rajagopal and Jayabalakrishnan, 2010). Recently, we have reported the interactional behavior of l ‐ascorbic acid and nicotinic acid (vitamin C and vitamin B3) in the mixed systems of surfactants at different temperatures (Banipal et al, 2019, 2020). Valuable information about the complex biological systems can be acquired from the precise study of thermodynamic and spectroscopic properties of mixed (surfactant + drug) system in the presence of amino acids.…”

Exploration of Interactions between Pyridoxine HCl (Vitamin B6) and {Hexadecyltrimethylammonium Bromide + Sodium Cholate (Trihydroxy Bile Salt)} Mixtures at T = (298.15 to 318.15) K: Physicochemical and Spectroscopic Approach

“…Micelles (the microscopic molecular assemblies), which imitate the microenvironment present in the biological systems, can be helpful to understand the naturally occurring processes. , The food and biomedical industries are anxious to design new colloidal-based delivery systems for several lipophilic bioactive compounds, that is, phytosterols, flavonoids, carotenoids, vitamins, and drugs as well as ω-3 fatty acids so as to encapsulate, prevent their physical and chemical degradation, and transport them to the desired site of action after ingestion . On account of their significance in the fields of biology and medicine, researchers have reported analogous studies in recent literature. , …”

“…19 On account of their significance in the fields of biology and medicine, researchers have reported analogous studies in recent literature. 20,21 Therefore, an attempt is made to explore the effect of pyridoxine HCl (vitamin B 6 ) on the physicochemical and spectroscopic properties of catanionic (HTAB + NaC) mixtures at varying temperatures (298. 15, 308.15, and 318.15) K. This study would provide insight into the nature of interactions persisting among the quarternary ammonium ions and biological detergents in the presence of vitamin B 6 inside the physiological environment.…”