Elucidating the role of reactive oxygen species metabolism and phenylpropanoid pathway during an incompatible interaction between apple-Venturia inaequalis host-pathosystem

Mansoor, Sheikh; Sakina, Aafreen; Mir, Mudasir Ahmad; Mir, Javid Iqbal; Wani, Ajaz Ahmad; Nabi, Sajad Un; Alyemeni, Mohammed Nasser; Chung, Yong Suk; Masoodi, Khalid Z.

doi:10.1016/j.sajb.2023.07.020

Cited by 6 publications

(3 citation statements)

References 49 publications

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“…The pathway starts with phenylalanine, which can be converted into aromatic compounds and phenylpropanoids in response to disease resistance ( Geng et al, 2020 ). In addition, phenylalanine ammonia-lyase (PAL) is a crucial enzyme in secondary phenylalanine metabolism and is widely studied in plant responses to biotic stresses ( Kurihara and Yamana, 2022 ; Mansoor et al, 2023 ). We observed that many DEGs and DAMs were enriched in the phenylalanine, tyrosine, and tryptophan biosynthesis pathways in both groups.…”

Section: Discussionmentioning

confidence: 99%

Integrated transcriptome and metabolome profiling reveals mechanisms underlying the infection of Cytospora mali in “Jin Hong” branches

Zhao,

Guo,

et al. 2024

Front. Microbiol.

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IntroductionValsa canker, caused by Cytospora mali, is a destructive disease in apple production. However, the mechanism by which apple defend against C. mali infection remains unclear.MethodsIn this study, the integrative transcriptional and metabolic analysis were used to investigate the responses of the ‘Jin Hong’ apple branches to the invasion of C. mali.Results and DiscussionResults showed that the differentially expressed genes were mainly enriched in the pathways of carbon metabolism, photosynthesis-antenna proteins, and biosynthesis of amino acids pathways. Additionally, the differentially accumulated metabolites were significantly enriched in aminoacyl-tRNA biosynthesis, fructose and mannose metabolism, and alanine, aspartate, and glutamate metabolism pathways. Conjoint analysis revealed that C. mali infection significantly altered 5 metabolic pathways, 8 highly relevant metabolites and 15 genes of apples. Among which the transcription factors WRKY and basic domain leucine zipper transcription family were induced, the α-linolenic acid and betaine were significantly accumulated in C. mali infected apple stems. This work presents an overview of the changes in gene expression and metabolic profiles in apple under the inoculation of C. mali, which may help to further screen out the mechanism of plant-pathogen interaction at the molecular level.

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Section: Discussionmentioning

confidence: 99%

Integrated transcriptome and metabolome profiling reveals mechanisms underlying the infection of Cytospora mali in “Jin Hong” branches

Zhao,

Guo,

et al. 2024

Front. Microbiol.

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“…reported that components containing phloridzin in apple waste have the strongest antifungal activity. Recently, Mansoor et al [ 40 ]. showed that the content of phloridzin significantly increased in apple plants infected with Venturia inaequalis , improving their defense ability.…”

Section: Discussionmentioning

confidence: 99%

Melatonin enhances resistance to Botryosphaeria dothidea in pear by promoting jasmonic acid and phlorizin biosynthesis

Xu,

Zhang,

Liang

et al. 2024

BMC Plant Biol

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Ring rot, caused by Botryosphaeria dothidea, is an important fungal disease of pear fruit during postharvest storage. Melatonin, as a plant growth regulator, plays an important role in enhancing the stress resistance of pear fruits. It enhances the resistance of pear fruits to ring rot by enhancing their antioxidant capacity. However, the underlying mechanism remains unclear. In this study, we examined the effect of melatonin on the growth of B. dothidea. Results showed that melatonin did not limit the growth of B. dothidea during in vitro culture. However, metabolomics and transcriptomics analyses of ‘Whangkeumbae’ pear (Pyrus pyrifolia) revealed that melatonin increased the activity of antioxidant enzymes, including peroxidase (POD), superoxide dismutase (SOD), and polyphenol oxidase (PPO), in the fruit and activated the phenylpropanoid metabolic pathway to improve fruit resistance. Furthermore, melatonin treatment significantly increased the contents of jasmonic acid and phlorizin in pear fruit, both of which could improve disease resistance. Jasmonic acid regulates melatonin synthesis and can also promote phlorizin synthesis, ultimately improving the resistance of pear fruit to ring rot. In summary, the interaction between melatonin and jasmonic acid and phlorizin enhances the antioxidant defense response and phenylpropanoid metabolism pathway of pear fruit, thereby enhancing the resistance of pear fruit to ring rot disease. Our results provide new insights into the application of melatonin in the resistance to pear fruit ring rot.

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“…In living cells, metabolic processes can give rise to ROS as by-products, and their enhanced level leads to a state of oxidative burst. In plants, recent studies have demonstrated an interest in the dual function of ROS [ 19 , 26 , 27 , 28 ]. In addition to its detrimental effects, ROS plays a significant role in signaling molecules to regulate the process of cell growth and development, apoptosis as well as stimulation of systemic response under biotic and abiotic stress.…”

Section: Mechanism Of Ros Productionmentioning

confidence: 99%

Heavy Metal Induced Oxidative Stress Mitigation and ROS Scavenging in Plants

Mansoor,

Ali,

Kour

et al. 2023

Plants

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Although trace elements are essential for life, environmental contamination due to metal accumulation and overuse in various sectors, such as healthcare, agriculture, industry, and cosmetics, poses significant health concerns. Exposure of plants to heavy metals leads to the overproduction of reactive oxygen species (ROS) due to their ability to change mitochondrial membrane permeability and restrict the action of ROS clearance enzymes in the cellular antioxidant system. The interaction of ROS with cellular membranes, heavy-metal-induced interactions directly or indirectly with different macromolecules, and signaling pathways leads to the accumulation of environmental pollutants and oxidative stress in exposed organisms. The heavy metal–ROS–cell signaling axis affects various pathological processes such as ATP depletion, excess ROS production, mitochondrial respiratory chain damage, decoupling of oxidative phosphorylation, and mitochondrial death. This review focuses on discussing the toxic effects of different heavy metals on plants, with particular emphasis on oxidative stress, its consequences, and mitigation strategies.

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Elucidating the role of reactive oxygen species metabolism and phenylpropanoid pathway during an incompatible interaction between apple-Venturia inaequalis host-pathosystem

Cited by 6 publications

References 49 publications

Integrated transcriptome and metabolome profiling reveals mechanisms underlying the infection of Cytospora mali in “Jin Hong” branches

Integrated transcriptome and metabolome profiling reveals mechanisms underlying the infection of Cytospora mali in “Jin Hong” branches

Melatonin enhances resistance to Botryosphaeria dothidea in pear by promoting jasmonic acid and phlorizin biosynthesis

Heavy Metal Induced Oxidative Stress Mitigation and ROS Scavenging in Plants

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