Elucidating the Role of O2 Uncoupling for the Adaptation of Bacterial Biodegradation Reactions Catalyzed by Rieske Oxygenases
Charlotte E. Bopp,
Nora M. Bernet,
Fabian Meyer
et al.
Abstract:Oxygenation of aromatic and aliphatic hydrocarbons by Rieske oxygenases
is the initial step of various biodegradation pathways for environmental
organic contaminants. Microorganisms carrying Rieske oxygenases are
able to quickly adapt their substrate spectra to alternative carbon
and energy sources that are structurally related to the original target
substrate, yet the molecular events responsible for this rapid adaptation
are not well understood. Here, we evaluated the hypothesis that reactive
oxygen species … Show more
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