Elucidating the Molecular Interactions between Lipids and Lysozyme: Evaporation Resistance and Bacterial Barriers for Dry Eye Disease
Deborah Lee,
Seoyoon Song,
Geonho Cho
et al.
Abstract:Dry eye disease (DED) is a chronic condition characterized
by ocular
dryness and inflammation. The tear film lipid layer (TFLL) is the
outermost layer composed of lipids and proteins that protect the ocular
surface. However, environmental contaminants can disrupt its structure,
potentially leading to DED. Although the importance of tear proteins
in the TFLL functionality has been clinically recognized, the molecular
mechanisms underlying TFLL–protein interactions remain unclear.
In this study, we investigated … Show more
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