Abstract:<p>Conventional wound healing assays are inadequate for evaluating the influence of symmetry on wound healing as they either offer poor geometrical control of the wounds created or fail to trigger a wound healing response in cell layers. To address these issues, herein we developed a novel CAD/CAM laser direct write photoablation assay that enables the generation of wounds with precisely defined and highly customizable geometries. As proof of principle, we biologically validated this assay to study the i… Show more
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