ELOVL2‐methylation and renal and cardiovascular event in patients with chronic kidney disease
Rima Obeid,
Patricia Rickens,
Gunnar Henrik Heine
et al.
Abstract:BackgroundMethylation of the Elongation Of Very Long Chain Fatty Acids‐Like 2 (ELOVL2) gene promoter may predict premature ageing and cardiovascular risk.MethodsWe studied the cross‐sectional associations between blood ELOVL2‐methylation and cardiovascular risk factors in 350 patients with chronic kidney disease (CKD) stage G2–G4 aged between 22 and 90 years. In a follow‐up study for a mean of 3.9 years, we investigated the association between baseline ELOVL2‐methylation and renal or cardiovascular events incl… Show more
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