“…In this study, patients who achieved optimal responses had significantly better long-term outcomes (EFS, FFS, and transformation-free survival (TFS)) at 3, 6, or 12 months compared to cases with warning and failure. However, like in the previous two studies [7,8], the authors of this study [9] could not demonstrate a significant OS difference between patients with optimal response and warning at 3, 6, or 12 months.…”