We study the Kaluza-Klein reduction of various 6d holomorphic theories. The KK reduction is analyzed in the BV formalism, resulting in theories that come from the holomorphic topological twist of 3d N = 2 supersymmetric field theories. Effective interactions of the KK theories at the classical level can be obtained at all orders using homotopy transfer theorem.We also analyze a deformation of the theories that comes from deforming the spacetime geometry to SL 2 (C) due to the brane back-reaction. We study the boundary chiral algebras for the various KK theories. Using Koszul duality, we argue that by properly choosing a boundary condition, the boundary chiral algebra coincides with the universal defect chiral algebra of the original theory. This perspective provides a unified framework for accessing the chiral algebras that arise from both twisted holography and celestial holography programs.