Ellagic acid inhibits gastric cancer cells by modulating oxidative stress and inducing apoptosis
Jian Zheng,
Chun-Feng Li
Abstract:Objective:
To evaluate the anticancer effect of ellagic acid on gastric cancer cells.
Methods:
MTT assay was used to evaluate the effect of ellagic acid at different concentrations (0.5-100 μg/mL) on gastric cancer AGS cells. RT-qPCR and Western blot analyses were applied to assess apoptosis (BCL-2, CASP-3, and BAX) and autophagy (LC3, ATG5, and BECN1) in AGS cells treated with ellagic acid. The expression of invasion-related markers including TP53, CDK… Show more
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