Elevation of Plasma Copeptin in Acute Myocardial Infarction in Pigs is Related to Changes in Mean Arterial Blood Pressure but not to Myocardial Ischemia
Abstract:Background: Copeptin increases early after myocardial infarction (MI). We used a porcine MI model with serial copeptin-testing and assessment of hemodynamic variables to evaluate the trigger for copetin-release and the liberation kinetics of copeptin in MI. Methods: AMI was induced by percutaneous transluminal coronary angioplasty (PTCA). Blood samples were taken in 30-minute intervals. Results: All animals (n=4) had a comparable infarction size (10.02 ± 2.11% of the left ventricle) and elevated troponin T lev… Show more
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