Elevation of Kiss2 and its receptor gene expression in the brain and pituitary of grass puffer during the spawning season

Shahjahan, Md.; Motohashi, Eiji; Doi, Hiroyuki; Ando, Hironori

doi:10.1016/j.ygcen.2010.07.008

Cited by 90 publications

(61 citation statements)

References 41 publications

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“…These results indicate that goldfish pituitary cells are potentially regulated by Kiss1 produced and/or released at the pituitary level. Likewise, the presence of Kiss immunoreactivity and/or mRNA in the pituitary has also been reported for other teleosts, including zebrafish and grass puffer [37,38], suggesting direct pituitary actions of Kiss may be present in other teleosts. Incubation of dispersed goldfish pituitary cells with synthetic goldfish Kiss1 (1)(2)(3)(4)(5)(6)(7)(8)(9)(10) (gKiss1 10 ) increased LH and GH released into culture medium by 30 min, as well as elevated LH and GH mRNA levels by 24 h [46].…”

Section: Introductionmentioning

confidence: 56%

“…In Morone bass species, Kiss2R and Kiss1R are differentially expressed by hypothalamic preoptic GnRH neurons and cells attached to GnRH neurons [50]. These and other results from brain Kiss and KissR expression experiments, as well as Kiss injection studies, suggest that, like mammals, central actions through modulation of GnRH neuronal secretion is a mechanism through which Kiss can affect reproduction, sexual maturation and/or peri-pubertal development in different fish species [2,37,38,42]. In goldfish, Kiss1R expression has been demonstrated for immunohistochemically identified gonadotrophs and somatotrophs and Kiss1 mRNA is also expressed in the goldfish pituitary [46].…”

Section: Introductionmentioning

confidence: 80%

“…However, with the detection of gKiss 10 expression in goldfish pituitary tissues [46], as well as in the pituitary tissues of other teleosts [37,38], that Kiss can act directly at the level of pituitary cells is likely to be of relevance. In summary, the present results provide important information on the direct pituitary actions of gKiss1 10 in a teleost fish, including how it may interact with native GnRHs and its intracellular signal transduction mechanisms in terms of stimulation of LH and GH release.…”

Section: Discussionmentioning

confidence: 99%

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Kisspeptin-1 directly stimulates LH and GH secretion from goldfish pituitary cells in a Ca2+-dependent manner

Chang¹,

Már²,

Wlasichuk³

et al. 2012

General and Comparative Endocrinology

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Section: Introductionmentioning

confidence: 56%

Section: Introductionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

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Kisspeptin-1 directly stimulates LH and GH secretion from goldfish pituitary cells in a Ca2+-dependent manner

Chang¹,

Már²,

Wlasichuk³

et al. 2012

General and Comparative Endocrinology

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“…After next 5 minutes the levels of LH in KISS-injected fish and the controls were not different. This difference in response to kisspeptin depending on the season when experiments were performed was expected as the seasonality in kisspeptin concentration or gene expression in the brain was shown in several fish species: grass puffer Takifugu niphobles (Shahjahan, Motohashi, Doi, & Ando, 2010), Nile tilapia Oreochromis niloticus (Parhar, Ogawa, & Sakuma, 2004), cobia Rachycentron canadum (Mohammed, Benninghoff, Holt, & Khan, 2007), grey mullet Mugil cephalus (Nocillado, Levavi-Sivan, Carrick, & Elizur, 2007) fathead minnow Pimephales promelas (Filby et al, 2008), Atlantic halibut Hippoglossus hipoglossus (Mechaly, Vińas, Murphy, Reith, & Piferrer, 2010), Senegalese sole Solea senegalensis (Mechaly, Vińas, & Piferrer, 2009) and zebrafish Danio rerio (Biran, Ben-Dor & Levavi-Sivan, 2008). Also in in vivo experiment Gosiewski et al (2015) demonstrated a different response to kisspeptin at the time of gonad recrudescence and at the time of natural spawning (depending on the stage of gonad maturity, i.e.…”

Section: Discussionmentioning

confidence: 80%

“…During that period the sensitivity of HPG axis (number of receptors and/or their affinity to the ligands) is lower (Jodo et al, 2005;Shahjahan et al, 2010) and the extended time to respond to exogenous hormone (hours, but not minutes) may be needed.…”

Section: Discussionmentioning

confidence: 99%

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Mikolajczyk¹,

Gosiewski²,

Chyb³

et al. 2018

Turk. J. Fish. Aquat. Sci.

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Kisspeptin plays a critical role in the control of reproduction and puberty onset in vertebrates, fish including. To demonstrate the pattern of LH secretory responses [spontaneous and stimulated by GnRH analogue (Des Gly 10 , D-Ala 6 ethylamide LHRH)] to single, intraperitoneal injection of human kisspeptin [metastin (45-54) amide], blood samples from mature Prussian carp females (at the time of gonad recrudescence and natural spawning) were collected at 5, 10, 15 and 30 minutes after injection. To test the influence of dopamine on kisspeptin action on LH release, the dopamine antagonistpimozide -was used together with kisspeptin and GnRH analogue. At the time of gonad recrudescence kisspeptin alone had no effect on LH secretion. At the time of natural spawning the transient increase of LH levels at 10 th minute post-injection was observed. Also the combination of kisspeptin and GnRHa increased LH levels in comparison to control fish at 10, 15 and 30 minutes after injections and at 10 th minute kisspeptin potentiated stimulatory effects of GnRHa. No influence of kisspeptin on the spontaneous, as well as GnRHa-stimulated LH release was observed in pimozide-treated fish. Presented data suggest that the short-term response to kisspeptin is dependent on the stage of gonadal maturity.

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Cloning and expression of tachykinins and their association with kisspeptins in the brains of zebrafish

Ogawa

Ramadasan

Goschorska

et al. 2012

J of Comparative Neurology

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The tachykinins are a family of neuropeptides, including substance P (SP), neurokinin A (NKA), and neurokinin B (NKB), that are encoded by the tac1 (SP and NKA) or tac2/3 (NKB) genes. Tachykinins are widely distributed in the central nervous system and have roles as neurotransmitters and/or neuromodulators. Recent studies in mammals have demonstrated the coexpression of NKB and kisspeptin and their comodulatory roles over the control of reproduction. We have recently identified two kisspeptin-encoding genes, kiss1 and kiss2, in teleosts. However, such relationship between tachykinins and kisspeptins has not been demonstrated in non-mammalian species. To determine the involvement of tachykinins in the reproduction in teleosts, we identified tac1 and two tac2 (tac2a and tac2b) sequences in the zebrafish genome using in silico data mining. Zebrafish tac1 encodes SP and NKA, whereas the tac2 sequences encode NKB and an additional peptide homologous to NKB (NKB-related peptide). Digoxigenin in situ hybridization in the brain of zebrafish showed tac1 mRNA-containing cells in the olfactory bulb, telencephalon, preoptic region, hypothalamus, mesencephalon, and rhombencephalon. The zebrafish tac2a mRNA-containing cells were observed in the preoptic region, habenula, and hypothalamus, whereas the tac2b mRNA-containing cells were predominantly observed in the dorsal telencephalic area. Furthermore, we examined the coexpression of tachykinins and two kisspeptin genes in the brain of zebrafish. Dual fluorescent in situ hybridization showed no coexpression of tachykinins mRNA with kisspeptins mRNA in hypothalamic nuclei or the habenula. These results suggest the presence of independent pathways for kisspeptins and NKB neurons in the brain of zebrafish.

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Elevation of Kiss2 and its receptor gene expression in the brain and pituitary of grass puffer during the spawning season

Cited by 90 publications

References 41 publications

Kisspeptin-1 directly stimulates LH and GH secretion from goldfish pituitary cells in a Ca2+-dependent manner

Kisspeptin-1 directly stimulates LH and GH secretion from goldfish pituitary cells in a Ca2+-dependent manner

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Cloning and expression of tachykinins and their association with kisspeptins in the brains of zebrafish

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