2017
DOI: 10.1172/jci.insight.92896
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Elevated urinary CRELD2 is associated with endoplasmic reticulum stress–mediated kidney disease

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Cited by 33 publications
(41 citation statements)
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“…Finally, CRELD2 is easily detected in unconcentrated urine from human ADTKD- UMOD patients, whereas urinary CRELD2 excretion is absent from all tested genetically unaffected controls by ELISA assay (Figure 2B). These results demonstrate the superb ability of CRELD2 to discriminate between controls and ADTKD patients with tubular ER stress [47]. …”
Section: Creld2 As a Urine Er Stress Biomarker In Both Mouse Models Amentioning
confidence: 77%
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“…Finally, CRELD2 is easily detected in unconcentrated urine from human ADTKD- UMOD patients, whereas urinary CRELD2 excretion is absent from all tested genetically unaffected controls by ELISA assay (Figure 2B). These results demonstrate the superb ability of CRELD2 to discriminate between controls and ADTKD patients with tubular ER stress [47]. …”
Section: Creld2 As a Urine Er Stress Biomarker In Both Mouse Models Amentioning
confidence: 77%
“…Recently, we have identified mesencephalic astrocyte-derived neurotrophic factor (MANF) and cysteine-rich with EGF-like domains 2 (CRELD2) as urinary ER stress biomarkers [46, 47]. …”
Section: Discovery Of Urinary Er Stress Biomarkers In Er Stress-mediamentioning
confidence: 99%
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