Elevated one hour with normal fasting and 2 h plasma glucose helps to identify those at risk for development of Type2 Diabetes-11 years observational study from south India

Kumpatla, Satyavani; Parveen, Rizwana; stanson, Shalini; Viswanathan, Vijay

doi:10.1016/j.dsx.2019.06.029

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…In a study on South Indian adults with an 11-year follow-up, it was observed that individuals with elevated 1 h-PPG levels had more tendencies for the development of diabetes mellitus. [20] Also, progression to diabetes mellitus was also higher in Indians with deranged 1 h-PPG values, as observed by Priya et al . in 1179 subjects.…”

Section: Discussionmentioning

confidence: 62%

Correlation of Carotid Intima-Media Thickness with One-hour Postload Plasma Glucose (1h-PPG) in Overweight and Obese North Indian Adults

Jesrani,

Gupta,

Kaur

et al. 2023

Apollo Medicine

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Background: Cardiovascular morbidities like arterial stiffness and atherosclerosis have a negative association with insulin resistance, which can be identified by carotid intima media thickness (CIMT) measurement. One-hour postload plasma glucose (1 h-PPG) is a novel marker for early identification of insulin resistance, but very few studies are available on its relationship with CIMT. Objective: To identify the correlation of CIMT with 1 h-PPG in overweight and obese adults without diabetes. Methods: Individuals not having known diabetes or other chronic illnesses were identified and subjected to the initial anthropometric analysis for body mass index (BMI) calculation. A standard oral glucose tolerance test was performed on individuals with a BMI of ≥25 kg/m2 for 1 h-PPG values, and a B-mode ultrasound scan of the neck was used for CIMT measurement. A Pearson’s correlation statistical test was applied for correlation identification. Results: A total of 94 nondiabetic individuals participated, of whom 55 (58.5%) were women. Mean age, BMI, and CIMT values of the study population were 38.8 (±8.09) years, 29.6 (±3.22) kg/m2, and 0.72 (±0.10) mm, respectively. Average 1 h-PPG levels were 150.7 (±21.11) mg/dl, and the Pearson’s coefficient (r) value with CIMT was 0.5792 (P < 0.05). Further, correlation analysis demonstrated an r-value of −0.0029 for BMI, −0.1293 for waist-hip ratio, −0.0047 for waist-height ratio, 0.3862 for glycated hemoglobin (HbA1c), and −0.2930 for 2 h-PPG. Conclusion: In euglycemic adults, the early insulin resistance defining parameter, i.e., 1 h-PPG levels had a consistent positive correlation with CIMT, which is a marker of the initial stages of atherosclerosis.

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Section: Discussionmentioning

confidence: 62%

Correlation of Carotid Intima-Media Thickness with One-hour Postload Plasma Glucose (1h-PPG) in Overweight and Obese North Indian Adults

Jesrani,

Gupta,

Kaur

et al. 2023

Apollo Medicine

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RSSDI endorses the IDF Position Statement on 1 h post load plasma glucose for diagnosis of intermediate hyperglycemia and type 2 diabetes

Sahay,

Mohan,

Agarwal

et al. 2024

Int J Diabetes Dev Ctries

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International Diabetes Federation Position Statement on the 1-hour post-load plasma glucose for the diagnosis of intermediate hyperglycaemia and type 2 diabetes

Bergman,

Manco,

Satman

et al. 2024

Diabetes Research and Clinical Practice

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Elevated one hour with normal fasting and 2 h plasma glucose helps to identify those at risk for development of Type2 Diabetes-11 years observational study from south India

Cited by 5 publications

References 17 publications

Correlation of Carotid Intima-Media Thickness with One-hour Postload Plasma Glucose (1h-PPG) in Overweight and Obese North Indian Adults

Correlation of Carotid Intima-Media Thickness with One-hour Postload Plasma Glucose (1h-PPG) in Overweight and Obese North Indian Adults

RSSDI endorses the IDF Position Statement on 1 h post load plasma glucose for diagnosis of intermediate hyperglycemia and type 2 diabetes

International Diabetes Federation Position Statement on the 1-hour post-load plasma glucose for the diagnosis of intermediate hyperglycaemia and type 2 diabetes

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Elevated one hour with normal fasting and 2 h plasma glucose helps to identify those at risk for development of Type2 Diabetes-11 years observational study from south India

Cited by 5 publications

References 17 publications

Correlation of Carotid Intima-Media Thickness with One-hour Postload Plasma Glucose (1h-PPG) in Overweight and Obese North Indian Adults

Correlation of Carotid Intima-Media Thickness with One-hour Postload Plasma Glucose (1h-PPG) in Overweight and Obese North Indian Adults

RSSDI endorses the IDF Position Statement on 1 h post load plasma glucose for diagnosis of intermediate hyperglycemia and type 2 diabetes

International Diabetes Federation Position Statement on the 1-hour post-load plasma glucose for the diagnosis of intermediate hyperglycaemia and type 2 diabetes

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Elevated one hour with normal fasting and 2 h plasma glucose helps to identify those at risk for development of Type2 Diabetes-11 years observational study from south India