“…Studies had shown either increases [54,55], or no changes [56,57] in activated T cell populations in psoriatic vs. control blood comparisons. Our results, from a severely affected patient population, show that psoriasis vulgaris appears to be different from the other autoimmune disorders and from controls since we found increases in CD25 and did not find increases of CD69 or HLA-DR on circulating T cells as found in other chronic autoimmune disorders [58][59][60].…”