2010
DOI: 10.1086/657314
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Elevated Influenza‐Related Excess Mortality in South African Elderly Individuals, 1998–2005

Abstract: These data suggest that the impact of seasonal influenza on mortality among elderly individuals may be substantially higher in an African setting, compared with in the United States, and highlight the potential for influenza vaccination programs to decrease mortality.

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Cited by 89 publications
(98 citation statements)
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“…Many respondents did not think that people could die from influenza. However, the rate of influenza‐attributable death among older adults in South Africa is several times higher than it is among older adults in the United States 4. This underestimation of influenza severity in the community may undermine its importance as a public health issue.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Many respondents did not think that people could die from influenza. However, the rate of influenza‐attributable death among older adults in South Africa is several times higher than it is among older adults in the United States 4. This underestimation of influenza severity in the community may undermine its importance as a public health issue.…”
Section: Discussionmentioning
confidence: 99%
“…Influenza infections are responsible for 43–67% of outpatient visits for influenza‐like illness during the peak of influenza season 3. Among South Africans of 65 years of age or older, the rate of excess mortality due to pneumonia and influenza is estimated at 340 deaths per 100 000 population;4 this influenza‐attributable mortality rate is even higher among young adults with AIDS in South Africa, at an estimated 570 deaths per 100 000 5. In addition, HIV‐positive South Africans have been shown to be at greater risk for severe influenza illness 6.…”
Section: Introductionmentioning
confidence: 99%
“…Young children, the elderly and those with other underlying health conditions such as HIV have an increased risk of developing complications of influenza, such as pneumonia 2, 3, 4…”
Section: Introductionmentioning
confidence: 99%
“…Mientras que durante las estaciones pandémicas, el incremento relativo en la tasa de mortalidad es superior para personas jóvenes (menores de 65 años) que para mayores de 65 años de edad. Nuestras estimaciones de exceso de mortalidad debido a influenza fueron sustanciales, especialmente en 2009 en el grupo de edad de menores de 65 años, que se caracterizó por la presencia de influenza A(H1N1)pdm 2009 29,[34][35][36] , y en 2007 en mayores de 65 años, asociado a la circulación de influenza A(H3N2), así como también fue evidenciado en otros estudios 14,[31][32][33]37 . Los factores que pueden explicar los patrones de mortalidad observadas es que personas mayores durante 2009 tuvieron susceptibilidad reducida debido a exposición pasada, ya fuese por infección natural o vacunación a una cepa H1 similar o una cepa que provee inmunidad protectora cruzada.…”
Section: Artículo Originalunclassified
“…En los años 2006, 2008 y 2010 no se produjo un exceso de mortalidad, años en los que se observó la circulación de virus influenza B y subtipo de influenza A (H1N1), que se conoce tienen baja severidad evidenciada por varios autores 14,[32][33][34][35][36][37][38][39][40] . Esto podría deberse a que en el caso de cepas A (H1N1) han circulado desde 1918, con un intervalo entre 1957 y 1977, y se ha ido adaptando a la población humana y viceversa 38 .…”
Section: Artículo Originalunclassified