Elevated end‐diastolic wall stress after acute myocardial infarction predicts adverse cardiovascular outcomes and longer hospital length of stay

Abstract

End-diastolic walls tress is a potential prognostic tool for risk stratifying STEMI patients, providing an assessment of the functional consequences of myocardial remodeling. It is predictive of MACE independent of LVEF, associated with longer hospitalizations, and correlates with galectin-3, a biomarker of cardiac remodeling.

Elevated myocardial wall stress after percutaneous coronary intervention in acute ST elevation myocardial infraction is associated with increased mortality

“…15 In 2018, we published data from 81 STEMI patients, and reported end-diastolic wall stress as a prognostic tool for short-term risk-stratification. 1 Current study expands on our previous research by studying larger patient cohort with a longer duration of follow up. This is important because post-ischemic cardiac adaptation involves chronic myocardial adaptation, and the therapeutic goals may need to be adapted accordingly.…”

“…This is important because post-ischemic cardiac adaptation involves chronic myocardial adaptation, and the therapeutic goals may need to be adapted accordingly. 1,16,17 Therefore, we have aimed to (a) evaluate the clinical utility of echocardiography based ventricular wall stress algorithms in long-term risk-stratification of patients with postischemic myocardial dysfunction, and (b) evaluate the additive utility of echocardiogram-derived ventricular wall stress over other common demographic and clinical parameters such as age and the extent of coronary artery disease.…”

Serum oxidative stress factors predict myocardial ischemia reperfusion injury after percutaneous coronary intervention in patients with acute myocardial infarction and type 2 diabetes mellitus

“…Acute myocardial infarction (AMI) results in ventricular remodeling in response to oxygen demand, which is characterized by left ventricular dilatation and elevated myocardial wall stress [1,2]. Percutaneous coronary interven-tion (PCI) has been regarded as a gold standard therapy for AMI therapy to restore coronary blood flow [3,4].…”