Elemental and Nutritional Analysis of Sea Buckthorn (<i>Hippophae rhamnoides</i>ssp.<i>turkestanica</i>) Berries of Pakistani Origin

Sabir, Syed Mubashar; Maqsood, H.; Hayat, Imran; Khan, Muhammad Qayyum; Khaliq, Abdul

doi:10.1089/jmf.2005.8.518

Cited by 55 publications

(33 citation statements)

References 9 publications

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“…The results obtained were in confirmation with the previous reports by Sabir et al, 2005. 14 The GCMS analysis of both the oil samples revealed presence of palmitoleic acid (6.72%), eicosanoic acid (11.18%), and LA (39.71%) in HR. It was also found rich in ALA ( Figure S1).…”

Section: Resultssupporting

confidence: 91%

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Comparison of Fatty Acid Profiling and RBC Membrane Stabilization Activity of Seabuckthorn (Hippophae rhamnoides and Hippophae salicifolia) Seed Oil

Dubey¹,

Ramana²,

Mishra³

2017

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Background: Seabuckthorn (SBT) is one of the most important plants of higher altitude in India and China. SBT seed oil is rich in Poly Unsaturated Fatty Acid (PUFA) which is present in a peculiar ratio capable of combating inflammation. Objective: To compare the physicochemical characteristics, fatty acid profiling and Red Blood Cell (RBC) membrane stabilization activity between two species of SBT seed oil; Hippophae rhamnoides (HR) and Hippophae salicifolia (HS) collected from Ladakh and Sikkim, India, respectively. Materials and Methods: GC-MS analysis was performed and effect of SBT seed oil was evaluated against heat and hypotonicity induced haemolysis of RBC. Protein denaturation assay was also conducted to check its probable role in chronic inflammation. Results: GC-MS analysis confirmed the presence of PUFA viz. Alpha linolenic acid (ALA) and Linoleic acid (LA) in SBT seed oil. Both significantly (p<0.05) inhibited heat and hypotonicity induced membrane destabilization in a concentration dependant manner. Maximum percentage inhibition of protein denaturation was observed at 3.6 μg/ml after incubation period of 4 hours. Conclusion: HR and HS have been proved to inhibit membrane destabilization with almost equal efficacy. Their efficacy against heat induced protein denaturation indicates that they may be useful in prevention and/or treatment of chronic inflammation as well. These findings may be attributed to the presence of PUFA. This study has contributed in establishing some preliminary evidence about PUFAs being the mainstay of their anti-inflammatory efficacy. However, in vivo studies are required to further validate the results of this study. cellular concentrations by increased n-6 and decreased n-3 PUFA content of the modern western diet. HR and HS seed oil contains the 18-carbon n-3 fatty acid, ALA, which can be converted after ingestion to the 20-carbon n-3 fatty acid, EPA. EPA is believed to act as a competitive inhibitor of AA conversion to prostaglandin E2 and leukotriene B4, thereby, decreasing the synthesis of one or both of these eicosanoids. Similar to the effect of n-3 fatty acids, inclusion of the 20-carbon n-9 fatty acid, eicosatrienoic acid 5 and OA 6 in the diet also results in decreased synthesis of LTB4. Treatment of inflammation includes extensive use of non-steroidal anti-inflammatory agents (NSAIDs). However, their use makes the patients more vulnerable to gastrointestinal and liver toxicities.8 Therefore, new anti-inflammatory drugs having alternative mechanisms are being searched as substitutes to NSAIDs. 9 Inflammation is a complicated biological response of vascular tissues to external detrimental stimuli and can either be acute or chronic. At the onset of an inflammatory process, the cells undergo activation and release inflammatory mediators such as histamine and serotonin.10 These mediators collectively cause elevated vasodilatation and permeability of measured and reconstituted as a 40% v/v suspension with isotonic buffer solution (10 mM sodium phosphate buf...

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Section: Resultssupporting

confidence: 91%

“…12 Saso et al, 1999 demonstrated that presence of PUFA such as AA, LA and ALA etc. inhibit heat induced protein denaturation 13,14 Hence, it becomes essential to assess the level of protein denaturation in presence of SBT seed oil to understand its potential in chronic inflammatory conditions.…”

Section: Inhibition Of Protein Denaturationmentioning

confidence: 99%

Comparison of Fatty Acid Profiling and RBC Membrane Stabilization Activity of Seabuckthorn (Hippophae rhamnoides and Hippophae salicifolia) Seed Oil

Dubey¹,

Ramana²,

Mishra³

2017

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“…Flavonoids, a large group of phenolic compounds (Sabir et al, 2005) with several well-documented biological activities beneficial to human health, are one of several important constituents of sea buckthorn berries (Barl et al, 2003). The significant position of flavonoids in our study was documented by high correlation coefficients (TFC-TAC, 0.8345; TFC-hydroxyl radical, 0.8930; TFC-nitric oxide, 0.9053; TFC-superoxide anion, 0.8635).…”

Section: Discussionmentioning

confidence: 55%

Antioxidant and radical scavenging activities in fruits of 6 sea buckthorn (Hippophae rhamnoides L.) cultivars

Rop¹,

Erċışlı²,

Mlček³

et al. 2014

Turk J Agric For

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Sea buckthorn (Hippophae rhamnoides L.) is a minor fruit crop. The most important breeding activities focused on the production of sea buckthorn fruits as a top-quality food product have been performed in Russia, Germany, and the Czech Republic. Over the past several decades, plant breeders have selected a number of cultivars that show excellent physical and nutritional properties. The aim of this study was to monitor and determine the total contents of phenols and flavonoids as well as antioxidant capacity and scavenging activity of methanolic extracts on reactive oxygen species and lipid peroxidation in some cultivars of sea buckthorn suitable for growing in Central Europe. Altogether, 6 cultivars of this fruit species presented total phenolic contents ranging from 8.62 g of gallic acid kg -1 of fresh mass to 14.17 g of gallic acid kg -1 of fresh mass. There were high correlations between the contents of phenols and flavonoids on the one hand and the antioxidant properties of sea buckthorn berries on the other. This study indicates that for Central European conditions, sea buckthorn is a promising fruit species that can be used for consumption due to its antioxidant properties.

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“…Sterols can be quantified by the colorimetric Liebermann-Burchard reaction (Wall, Kelley, 1947;Sabir et al, 2005), which is positive with stenols and negative with stanols (Brooks, 1970).…”

Section: Introductionmentioning

confidence: 99%

Production and characterization of alginate-starch-chitosan microparticles containing stigmasterol through the external ionic gelation technique

Fujiwara

Campos

Costa

et al. 2013

Braz. J. Pharm. Sci.

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Stigmasterol -a plant sterol with several pharmacological activities -is susceptible to oxidation when exposed to air, a process enhanced by heat and humidity. In this context, microencapsulation is a way of preventing oxidation, allowing stigmasterol to be incorporated into various pharmaceutical forms while increasing its absorption. Microparticles were obtained using a blend of polymers of sodium alginate, starch and chitosan as the coating material through a one-stage process using the external gelation technique. Resultant microparticles were spherical, averaging 1.4 mm in size. Encapsulation efficiency was 90.42% and method yield 94.87%. The amount of stigmasterol in the oil recovered from microparticles was 9.97 mg/g. This technique proved feasible for the microencapsulation of stigmasterol.Uniterms: Stigmasterol/ microencapsulation. Microencapsulation. Sodium alginate/drugs coating. Chitosan/drugs coating. Starch/drugs coating. Natural polymers/drugs coating.O estigmasterol, um fitoesterol com diversas atividades farmacológicas, é suscetível à oxidação quando exposto ao ar, calor e umidade. Neste contexto, a microencapsulação é uma forma de proteção contra oxidação, permitindo a incorporação do estigmasterol em diversas formas farmacêuticas e aumentar sua absorção. As micropartículas foram obtidas por gelificação iônica externa, em uma etapa, utilizando como revestimento polímeros naturais de alginato de sódio, amido de milho e quitosana. As micropartículas apresentaram formato esférico com tamanho aproximado de 1,4 mm. O rendimento foi de 94,87% e a eficiência média de encapsulação de 90,42%. A quantidade de estigmasterol no óleo recuperado das micropartículas foi de 9,97 mg/g. O método mostrou-se viável para a microencapsulação do estigmasterol.Unitermos: Estigmasterol/microencapsulação. Microencapsulamento. Alginato de sódio/revestimento de fámacos. Quitosana/revestimento de fámacos. Amido/revestimento de fámacos. Polímeros naturais/ revestimento de fámacos.

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Elemental and Nutritional Analysis of Sea Buckthorn (Hippophae rhamnoidesssp.turkestanica) Berries of Pakistani Origin

Cited by 55 publications

References 9 publications

Comparison of Fatty Acid Profiling and RBC Membrane Stabilization Activity of Seabuckthorn (Hippophae rhamnoides and Hippophae salicifolia) Seed Oil

Comparison of Fatty Acid Profiling and RBC Membrane Stabilization Activity of Seabuckthorn (Hippophae rhamnoides and Hippophae salicifolia) Seed Oil

Antioxidant and radical scavenging activities in fruits of 6 sea buckthorn (Hippophae rhamnoides L.) cultivars

Production and characterization of alginate-starch-chitosan microparticles containing stigmasterol through the external ionic gelation technique

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