“…Recent studies have demonstrated that intra and inter-aggregate dipolar interaction effects are renowned for modifying the heating efficacy of the MNPs 20 . However, despite achieving magnetic nanoparticles with improved functionalities, dispersibility, and the challenge of obtaining MNPs with enhanced functionalities/dispersibility and high SAR still persists 21 , 22 . Notably, dextran and chitosan-coated Fe 3 O 4 MNPs stand out as excellent options for clinical trials in hyperthermia applications due to their non-antigenic, biocompatible, bio-functional, and biodegradable nature 17 , 23 .…”