Element fractionation analysis for infant formula and food additives by inductively coupled plasma optical emission spectrometry

Bağdat, Sema; Baran, Eda Köse; Tokay, Feyzullah

doi:10.1111/ijfs.12312

Cited by 10 publications

(3 citation statements)

References 19 publications

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“…Most products that we tested were supplemented with Mn, but the unsupplemented dairy infant formula with the minimum Mn concentration (230 µg/L) would supply 29 times the daily Mn intake as breast milk for a 3-week-old and approximately 47 times the AI for Mn for this age stage. Cow and goat milks generally contain higher concentrations of Mn than human breast milk (Table 1) [20,108,109], and soy and rice proteins have even higher Mn concentrations [110,111], so it is highly unlikely that there is ever a need for Mn supplementation of infant formulas or young child nutritional beverage products in order to prevent Mn deficiency or achieve nutritional adequacy.…”

Section: Manganese Deficiency Is Highly Unlikely With Either Exclusivmentioning

confidence: 99%

Estimating daily intakes of manganese due to breast milk, infant formulas, or young child nutritional beverages in the United States and France: Comparison to sufficiency and toxicity thresholds

Mitchell¹,

Frisbie

Roudeau

et al. 2020

Preprint

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Laboratories provided no input in choosing the subject matter of this project, the hypotheses that were tested, the method of analysis, the research findings, the decision to publish, or the manner of disseminating the results. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Highlights1. Mn deficiency is unlikely with exclusive breast milk or infant formula feeding.2. Breast milk Mn mean intake is 1.2 µg/kg/day (3 weeks)-0.16 µg/kg/day (18 months).3. Formula Mn intake range is 130 µg/kg/day (3 weeks)-4.8 µg/kg/day (18 months). 4. Formula products reconstituted with 250 µg Mn/L water may exceed 140 µg Mn/kg/day. 5. Formula products may surpass regulatory tolerable daily intake levels for Mn. Abstract BackgroundAlthough manganese (Mn) is an essential nutrient, recent research has revealed that excess Mn in early childhood may have adverse effects on neurodevelopment. MethodsWe estimated daily total Mn intake due to breast milk at average body weights by reviewing reported concentrations of breast milk Mn and measurements of body weight and breast milk intake at 3 weeks, 4.25 months, 7 months, and 18 months. We compared these figures to the Mn content measured in 44 infant, follow-up, and toddler formulas purchased in the United States and France. We calculated Mn content of formula products made with ultra-trace elemental analysis grade water (0 µg Mn/L) and with water containing 250 µg Mn/L, a concentration which is relatively high but less than the World Health Organization Health-based value of 400 µg Mn/L or the United States Environmental Protection Agency Health Advisory of 350 µg Mn/L. ResultsEstimated mean daily Mn intake from breast milk ranged from 1.2 µg Mn/kg/day (3 weeks) to 0.16 µg Mn/kg/day (18 months), with the highest intakes at the youngest age stage we considered, 3 weeks. Estimated daily Mn intake from formula products reconstituted with 0 µg Mn/L water ranged from 130 µg Mn/kg/day (3 weeks) to 4.8 µg Mn/kg/day (18 months) with the highest intakes at 3 weeks. Formula products provided 28 to 520 times greater than the mean daily intake of Mn from breast milk for the 4 age stages that we considered. Estimated daily Mn intake from formula products reconstituted with water containing 250 µg Mn/L ranged from 12 µg Mn/kg/day to 170 µg Mn/kg/day, which exceeds the United States Environmental Protection Agency Reference Dose of 140 µg Mn/kg/day for adults. ConclusionsMn deficiency is highly unlikely with exclusive breast milk or infant formula feeding, but established tolerable daily intake levels for Mn may be surpassed by some of these products when following labeled instructions.

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Section: Manganese Deficiency Is Highly Unlikely With Either Exclusivmentioning

confidence: 99%

Estimating daily intakes of manganese due to breast milk, infant formulas, or young child nutritional beverages in the United States and France: Comparison to sufficiency and toxicity thresholds

Mitchell¹,

Frisbie

Roudeau

et al. 2020

Preprint

View full text Add to dashboard Cite

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“…The most widely published techniques for elemental analysis of infant formula are inductively coupled plasma optical emission spectrometry (ICP/OES) [16], electrothermal atomic absorption spectrometer (ETAAS) [17], flame and graphite furnace atomic absorption spectrometry (GF-AAS) [18,19], and inductively coupled plasma mass spectrometry (ICP-MS) [10,20,21]. Furthermore, elemental levels in milk powder formulations for infants and cereals have been successfully determined by energy dispersive X-ray fluorescence (EDXRF), and wavelength dispersive X-ray fluorescence (WDXRF) [22,23].…”

Section: Introductionmentioning

confidence: 99%

Assessment of some element content and potential health risks in infant formulas available in Turkish markets

Öztürk

Çalışkan

Akıncı

et al. 2023

Turkish Journal of Analytical Chemistry

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The determination of the composition of some essential and toxic elements in commercial infant food formulas is important for providing safe food for infants. These formulas play an important role in infant nutrition, and understanding their contribution to the dietary intake of infants is crucial. In this study, the concentrations of essential and toxic elements (Pb, Ni, Cd, Al, Cr, Cu, Fe, Mn, Zn, Co) in infant formulas were determined using high-resolution continuum-source flame atomic absorption spectrometry (HR CS FAAS) and have been evaluated for health risk. The measured values for concentrations from lowest to highest were (in mg/kg): 36.38-77.45 (Zn),

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“…Various sample preparation protocols have been utilized prior to element detection for food samples. Liquid-liquid extraction, dry ashing, open vessel wet digestion and closed vessel wet digestion are some of the most commonly used sample preparation procedures for various samples including edible oils, milk, food additives, dairy products, frozen and canned foods [15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Determination of Some Elements in Canned and Frozen Vegetables sold in Balıkesir (Türkiye) Markets and Nutritional Assessment

Tokay

2022

ADYU J SCI

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In this work, determination of some elements including Pb, Ni, Ba, Fe, Zn, Mg, Mn, Al, Cu, Mo, Ca, B, Cr, Cd, V and Co were carried out in some canned and frozen vegetable samples sold in Balıkesir, Türkiye. The study covered randomly chosen 13 canned and frozen samples such as green peas, okra, shell bean, sweet corn, green beans, garniture and tomato paste. Mineralization of the samples was achieved using microwave assisted wet digestion in closed vessels. The element contents were determined using ICP OES. The element contents were between 0.16-1.86 mg kg-1 for Ni; 0.33-5.02 mg kg-1 for Ba; 4.20-32.22 mg kg-1 for Fe; 1.65-14.64 mg kg-1 for Zn; 124.83-1016.79 mg kg-1 for Mg; 0.87-4.99 mg kg-1 for Mn; 0.32-1.74 mg kg-1 for Al; 0.78-14.97 mg kg-1 for Cu; 0.38-4.24 mg kg-1 for Mo; 42.60-1607.40 mg kg-1 for Ca and 0.96-7.56 mg kg-1 for B. Additionally, Pb was determined in only frozen green peas as 1.3±0.1 mg kg-1. In general, the highest element contents were found in frozen samples. In terms of nutritional assessment, estimated daily intakes of the elements were compared with recommended dietary allowances (RDA), nutrition reference values (TFC) and daily tolerable upper intake levels (UL) which were established by World Health Organization, Turkish Food Codex and Institute of Medicine, respectively. The results showed that the element contents of the analysed samples did not exceeded the permissible limits set by various health organizations. It is concluded that the contamination of these products may be an important threatening for public health. Therefore, monitoring of these samples should be a vital strategy for food industry.

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Element fractionation analysis for infant formula and food additives by inductively coupled plasma optical emission spectrometry

Cited by 10 publications

References 19 publications

Estimating daily intakes of manganese due to breast milk, infant formulas, or young child nutritional beverages in the United States and France: Comparison to sufficiency and toxicity thresholds

Estimating daily intakes of manganese due to breast milk, infant formulas, or young child nutritional beverages in the United States and France: Comparison to sufficiency and toxicity thresholds

Assessment of some element content and potential health risks in infant formulas available in Turkish markets

Determination of Some Elements in Canned and Frozen Vegetables sold in Balıkesir (Türkiye) Markets and Nutritional Assessment

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