Elektronenmikroskopische Untersuchungen der Aorta des Kaninchens

Seifert, Klaus

doi:10.1007/bf00350482

Cited by 23 publications

(3 citation statements)

References 37 publications

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Section: Aortamentioning

confidence: 99%

“…The general structure of the rabbit aorta has been described previously (Bierring and Kobayasi, 1963 ;Seifert, 1963 ;Stein et al ., 1969) and we shall summarize only those observations pertinent to the distribution of SR . In all major aspects, the distribution of SR in AO smooth muscle resembled its distribution in the MPA . In transverse section, stacked tubules of rough and smooth SR were present ( Figs .…”

Section: Aortamentioning

confidence: 99%

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Sarcoplasmic Reticulum and Excitation-Contraction Coupling in Mammalian Smooth Muscles

Devine

Somlyo

1972

The Journal of Cell Biology

522

274

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The sarcoplasmic reticulum (SR) was studied in the smooth muscles of rabbit main pulmonary artery, mesenteric vein, aorta, mesenteric artery, taenia coli, guinea pig mesenteric artery, and human uterus, and correlated with contractions of the smooth muscles in Cafree media . S R volumes, were determined in main pulmonary artery (5 .1 %), aorta (5%0), portal-anterior mesenteric vein (2 .2%), taenia coli (2%), and mesenteric artery (1 .8%) : because of tangentially sectioned membranes these estimates are subject to a correction factor of up to +50% of the values measured . Smooth muscles that contained a relatively large volume of SR maintained significant contractile responses to drugs in the virtual absence of extracellular calcium at room temperatures, while smooth muscles that had less SR did not . The unequal maximal contractions of main pulmonary artery elicited by different drugs were also observed in Ca-free, high potassium-depolarizing solution, indicating that they were secondary to some mechanism independent of changes in membrane potential or calcium influx . Longitudinal tubules of SR run between and are fenestrated about groups of surface vesicles separated from each other by intervening dense bodies . Extracellular markers (ferritin and lanthanum) entered the surface vesicles, but not the SR. The peripheral SR formed couplings with the surface membrane : the two membranes were separated by gaps of approximately 10 nm traversed by electron-opaque connections suggestive of a periodicity of approximately 20-25 nm . These couplings are considered to be the probable sites of electromechanical coupling in twitch smooth muscles . Close contacts between the SR and the surface vesicles may have a similar function, or represent sites of calcium extrusion . The presence of both thick and thin myofilaments and of rough SR in smooth muscles supports the dual, contractile and morphogenetic, function of smooth muscle .

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Section: Aortamentioning

confidence: 99%

Section: Aortamentioning

confidence: 99%

Sarcoplasmic Reticulum and Excitation-Contraction Coupling in Mammalian Smooth Muscles

Devine

Somlyo

1972

The Journal of Cell Biology

522

274

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“…Die Endothelzellen von Arterien und Venen bilden eine geschlossene Schicht (85,20,95,33,62,125,126,68,97,23). Auch dort, wo die Zellen nur eine Dicke von wenigen jum haben, zeigen sie nicht die für viele Kapillargebiete typischen Poren (117).…”

Section: D Ie Endothelstelleunclassified

Die Feinstruktur der Gefäßwände

Reale¹,

Ruska²

1965

J Vasc Res

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Electron microscopic localization of calcium in vascular smooth muscle

et al. 1975

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Potassium pyroantimonate has been employed in this study to localize calcium in the vascular smooth muscle of the thoracic aorta of the rabbit. The pyroantimonate ion precipitates sodium, magnesium and calcium. Incubation of theisolated thoracic aorta in a high potassium bathing medium which does not contain sodium, magnesium or calcium depletes the tissue of sodium. Addition of 10.8 mM CaC12 to the incubation medium results in well-localized depositions of reaction product, presumably that of calcium pyroantimonate, in mitochondria, sarcoplasmic reticulum, and at the plasma membrane. Some or all of these organelles may, therefore, play a vital role in the contraction-relaxation cycle of vascular smooth muscle.

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Elektronenmikroskopische Untersuchungen der Aorta des Kaninchens

Cited by 23 publications

References 37 publications

Sarcoplasmic Reticulum and Excitation-Contraction Coupling in Mammalian Smooth Muscles

Sarcoplasmic Reticulum and Excitation-Contraction Coupling in Mammalian Smooth Muscles

Die Feinstruktur der Gefäßwände

Electron microscopic localization of calcium in vascular smooth muscle

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