Electrospun poly (vinyl alcohol) nanofibers incorporating caffeic acid/cyclodextrins through the supramolecular assembly for antibacterial activity

Narayanan, Vimalasruthi; Alam, Manawwer; Ahmad, Naushad; Balakrishnan, Suganya Bharathi; Ganesan, Vigneshkumar; Shanmugasundaram, Esakkimuthu; Rajagopal, Brindha; Stalin, T.

doi:10.1016/j.saa.2020.119308

Cited by 15 publications

(2 citation statements)

References 61 publications

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“…Their formulation was based on the association of poly(vinyl alcohol) (PVA) with caffeic acid (CA)/β-CD and γ-CD inclusion complexes. Its antibacterial activity was demonstrated against the Gram-positive bacteria of E-coli and Gram-negative bacteria of S. aureus [ 129 ]. The versatility of the combination of electrospinning with CD encapsulation has been widely discussed in the recent literature [ 68 ].…”

Section: Methods Of Incorporating Cds In Polymer-based Active Food Packagingmentioning

confidence: 99%

Cyclodextrins in Polymer-Based Active Food Packaging: A Fresh Look at Nontoxic, Biodegradable, and Sustainable Technology Trends

et al. 2021

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Using cyclodextrins (CDs) in packaging technologies helps volatile or bioactive molecules improve their solubility, to guarantee the homogeneous distribution of the complexed molecules, protecting them from volatilization, oxidation, and temperature fluctuations when they are associated with polymeric matrices. This technology is also suitable for the controlled release of active substances and allows the exploration of their association with biodegradable polymer targeting to reduce the negative environmental impacts of food packaging. Here, we present a fresh look at the current status of and future prospects regarding the different strategies used to associate cyclodextrins and their derivatives with polymeric matrices to fabricate sustainable and biodegradable active food packaging (AFP). Particular attention is paid to the materials and the fabrication technologies available to date. In addition, the use of cutting-edge strategies, including the trend of nanotechnologies in active food packaging, is emphasized. Furthermore, a critical view on the risks to human health and the associated updated legislation is provided. Some of the more representative patents and commercial products that currently use AFP are also listed. Finally, the current and future research challenges which must be addressed are discussed.

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Section: Methods Of Incorporating Cds In Polymer-based Active Food Packagingmentioning

confidence: 99%

Cyclodextrins in Polymer-Based Active Food Packaging: A Fresh Look at Nontoxic, Biodegradable, and Sustainable Technology Trends

et al. 2021

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“…In another work, the same research group incorporated the CA derivate CAPE in electrospun microfibers composed of poly(3-hydroxybutirrate) and PVP, demonstrating a good anti-oxidant activity and their ability to inhibit the adhesion of pathogens [ 149 ]. Similarly, CA and cyclodextrin were encapsulated in poly (vinyl alcohol) nanofibers, increasing the resulting antimicrobial activity [ 215 ]. Poly(ε-caprolactone) fibrous mats loaded with CA were able to stimulate the proliferation and spreading of normal human dermal fibroblast-neonatal (NHDF-neo) cells and showed high antimicrobial activity [ 216 ].…”

Section: Hydroxycinnamic Acids and Derivatives: Advanced Formulationsmentioning

confidence: 99%

Hydroxycinnamic Acids and Derivatives Formulations for Skin Damages and Disorders: A Review

et al. 2021

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Alterations of skin homeostasis are widely diffused in our everyday life both due to accidental injuries, such as wounds and burns, and physiological conditions, such as late-stage diabetes, dermatitis, or psoriasis. These events are locally characterized by an intense inflammatory response, a high generation of harmful free radicals, or an impairment in the immune response regulation, which can profoundly change the skin tissue’ repair process, vulnerability, and functionality. Moreover, diabetes diffusion, antibiotic resistance, and abuse of aggressive soaps and disinfectants following the COVID-19 emergency could be causes for the future spreading of skin disorders. In the last years, hydroxycinnamic acids and derivatives have been investigated and applied in several research fields for their anti-oxidant, anti-inflammatory, and anti-bacterial activities. First, in this study, we give an overview of these natural molecules’ current source and applications. Afterwards, we review their potential role as valid alternatives to the current therapies, supporting the management and rebalancing of skin disorders and diseases at different levels. Also, we will introduce the recent advances in the design of biomaterials loaded with these phenolic compounds, specifically suitable for skin disorders treatments. Lastly, we will suggest future perspectives for introducing hydroxycinnamic acids and derivatives in treating skin disorders.

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Preparation of gallic acid functionalized polyvinyl alcohol/β‐cyclodextrin‐silver nanoparticles cast film as an antimicrobial and antioxidant agent

Narayanan,

Govindasamy,

Shanmugasundram

et al. 2023

J of Applied Polymer Sci

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In recent studies, researchers have been dedicated to the synthesis of silver nanoparticles (AgNPs) that can be adjusted in size, owing to their unique physical and chemical properties. In this study, AgNPs with well‐defined and stable characteristics are successfully functionalized with Gallic acid (GA) within a polymer matrix consisting of polyvinyl alcohol/β‐cyclodextrin polymeric biofilms (BFs) using a casting approach. To evaluate the particle size, functional groups, and crystallinity of the AgNPs, various techniques including UV, FT‐IR, TEM, and XRD are employed. The prepared BF films (BFs) are comprehensively analyzed for mechanical strength, color ratio, swelling ratio, surface morphology, elemental ratio, thermal behavior, and water wettability using stress–strain analysis, spectrophotometer color lab, SEM, EDAX, TGA, and contact angle techniques. Furthermore, the antimicrobial properties of the BFs are also investigated, along with their antioxidant activity assessed through the DPPH radical assay. The multifunctional BFs exhibited promising potential as antimicrobial agents for food preservation.

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Electrospun poly (vinyl alcohol) nanofibers incorporating caffeic acid/cyclodextrins through the supramolecular assembly for antibacterial activity

Cited by 15 publications

References 61 publications

Cyclodextrins in Polymer-Based Active Food Packaging: A Fresh Look at Nontoxic, Biodegradable, and Sustainable Technology Trends

Cyclodextrins in Polymer-Based Active Food Packaging: A Fresh Look at Nontoxic, Biodegradable, and Sustainable Technology Trends

Hydroxycinnamic Acids and Derivatives Formulations for Skin Damages and Disorders: A Review

Preparation of gallic acid functionalized polyvinyl alcohol/β‐cyclodextrin‐silver nanoparticles cast film as an antimicrobial and antioxidant agent

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