Electrospun Nanofibers for Sensors

Li, Yan; Abedalwafa, Mohammed Awad; Tang, Liqin; Li, De; Wang, Lu

doi:10.1016/b978-0-323-51270-1.00018-2

Cited by 32 publications

(22 citation statements)

References 121 publications

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“…In recent decades, submicron fibers have been steadily gaining the interest of researchers and the industry alike [ 1 ]. The unique properties and tailorable microstructure of submicron fibers make them useful in a range of applications, such as wound dressings [ 2 ], drug delivery platforms [ 3 , 4 ], energy materials [ 5 , 6 ], sensors [ 7 ], and filtration materials [ 8 , 9 , 10 ]. Submicron fibers of biocompatible and biodegradable polymers are also of particular interest in the field of tissue engineering and regenerative medicine [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Solution Blow Spinning of Polycaprolactone—Rheological Determination of Spinnability and the Effect of Processing Conditions on Fiber Diameter and Alignment

2021

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The growing popularity of solution blow spinning as a method for the production of fibrous tissue engineering scaffolds and the vast range of polymer–solvent systems available for the method raises the need to study the effect of processing conditions on fiber morphology and develop a method for its qualitative assessment. Rheological approaches to determine polymer solution spinnability and image analysis approaches to describe fiber diameter and alignment have been previously proposed, although in a separate manner and mostly for the widely known, well-researched electrospinning method. In this study, a series of methods is presented to determine the processing conditions for the development of submicron fibrous scaffolds. Rheological methods are completed with extensive image analysis to determine the spinnability window for a polymer–solvent system and qualitatively establish the influence of polymer solution concentration and collector rotational speed on fiber morphology, diameter, and alignment. Process parameter selection for a tissue engineering scaffold target application is discussed, considering the varying structural properties of the native extracellular matrix of the tissue of interest.

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Section: Introductionmentioning

confidence: 99%

Solution Blow Spinning of Polycaprolactone—Rheological Determination of Spinnability and the Effect of Processing Conditions on Fiber Diameter and Alignment

2021

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“…Currently, there are five main types of 3D printing methods, fused deposition modeling (FDM), selective laser sintering (SLS), direct write (DW), stereolithography (SLA), and material jetting (MJ; Figure 8). 70–72 3D printing has been proven to have some limitations when it comes to nylon. One example is the technology's inability to produce fibers and tubes.…”

Section: D Printing For Manufacturing Of Biomedical Devicesmentioning

confidence: 99%

Nylon—A material introduction and overview for biomedical applications

Shakiba

Ghomi

Khosravi

et al. 2021

Polymers for Advanced Techs

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Nylon is a human‐made material and has been applied in many industrial fields. This literature review explores the use of nylon in biomedical applications and discusses the properties and three‐dimensional (3D) printability of this material. Nylon is studied due to its versatility as an engineering plastic that can be easily transformed into fibers, films, and molded parts. Due to nylon's biocompatible nature, it has desirable chemical stability and tunable mechanical properties making this material and its derivatives widely used as sutures, catheters, dentures, and so on. However, the interactions between nylon and human body tissues have yet to be fully understood. Nevertheless, nylon is hybridized with different materials and used as skin dressings. In recent years, nylon composites have been actively researched in tissue engineering as an alternative to metallic implants with an appropriate bioactivity potential for bone growth. As nylon is supposed to be in contact with the tissue for a long time, hence researchers are developing antimicrobial strategies for the nylon materials to even promote their potential a step further. The 3D printing of nylon is currently confined to specific applications due to the printing technology's current limitations.

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“…Electrospinning is based on an electrohydrodynamic process in which fibers ranging from nm to µM are produced by uniaxial electric stretching and elongation of a viscoelastic solution [12][13][14]. The nanofibrous membranes are featured with a high surface-to-volume ratio, interconnected porous structure, low barrier to diffusion, and adjustable functionality [12][13][14][15]. These properties enable the design of hybrid and composite nanofibroussensing films with remarkable sensitivity and selectivity for several analytes [16].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Detection of Bisphenol A by Tyrosinase Immobilized on Electrospun Nanofibers Decorated with Gold Nanoparticles

et al. 2021

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Bisphenol A (BPA) is an endocrine-disrupting chemical (EDC) employed in industrial processes that causes adverse effects on the environment and human health. Sensitive and inexpensive methods to detect BPA are therefore needed. In this paper, we describe an electrochemical biosensor for detecting low levels of BPA using polymeric electrospun nanofibers of polyamide 6 (PA6) and poly(allylamine hydrochloride) (PAH) decorated with gold nanoparticles (AuNPs), namely, PA6/PAH@AuNPs, which were deposited onto a fluorine-doped tin oxide (FTO) substrate. The hybrid layer was excellent for the immobilization of tyrosinase (Tyr), which allowed an amperometric detection of BPA with a limit of detection of 0.011 μM in the concentration range from 0.05 to 20 μM. Detection was also possible in real water samples with recoveries in the range of 92–105%. The improved sensing performance is attributed to the combined effect of the large surface area and porosity of PA6/PAH nanofibers, the catalytic activity of AuNPs, and oxidoreductase ability of Tyr. These results provide a route for novel biosensing architectures to monitor BPA and other EDCs in water resources.

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Electrospun Nanofibers for Sensors

Cited by 32 publications

References 121 publications

Solution Blow Spinning of Polycaprolactone—Rheological Determination of Spinnability and the Effect of Processing Conditions on Fiber Diameter and Alignment

Solution Blow Spinning of Polycaprolactone—Rheological Determination of Spinnability and the Effect of Processing Conditions on Fiber Diameter and Alignment

Nylon—A material introduction and overview for biomedical applications

Electrochemical Detection of Bisphenol A by Tyrosinase Immobilized on Electrospun Nanofibers Decorated with Gold Nanoparticles

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