Electrospun Biomaterial for Biomedical Application

Abstract

SUMMARYNanostructured fibrous materials have been made more readily available in large part owing to recent advances in electrospinning and related technologies. Development of nanofibers by using the technique of electrospinning is having a new momentum. The nonwoven structure has unique features, including interconnected pores and a very large surface-tovolume ratio, which enable such nanofibrous scaffolds to have many biomedical and industrial applications, such as tissue engineering, wound dressing, enzyme immobilization and drug delivery. The chemical composition of electrospun membranes can be adjusted through the use of different polymers, In this paper, nanoscaffolds developed by using electrospinning and its applications in tissue engineering, drug delivery and wound healing are reviewed.

Synthesis, characterization and biological evaluation of chromen and pyrano chromen-5-one derivatives impregnated into a novel collagen based scaffold for tissue engineering applications

“…1,2 Tissue engineering is an emerging eld offering novel perspectives in the treatment of damaged or diseased organs. 3,4 Tissue engineering mostly requires the material to be biocompatible, 5 nontoxic, 6 low antigenicity 7 and noninammatory, 8,9 which is more important to design and develop a degradable material based on collagen. 10,11 The application of the collagen scaffold material for the tissue engineering eld 12 with cell attachment and proliferation makes the scaffold function as an extra cellular matrix.…”

Co-electrospun Nanofibrous Membranes of Collagen and Zein for Wound Healing

“…In recent years, electrospun polymeric nanofibers have been shown great potential as dressing materials for wound healing. − Typically, such materials have high porosity with excellent pore-interconnectivity, which is particularly important for exuding fluid from the wound. The inherent small pores and high specific surface area enable them to inhibit the invasion of exogenous microorganisms and assist the control of fluid drainage .…”