Electrospinning of poly(butylene-carbonate):Effect of Solvents on the Properties of the Nanofibers Film

Liu, Siwen; Song, Xue; Shao, Chenghua; Zeng, Peng; Lu, Xinkun; Shen, Xinyuan; Yang, Qing

doi:10.1016/s1452-3981(23)11025-x

Cited by 29 publications

(2 citation statements)

References 22 publications

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“…The polymer liquid is stretched by the charges collected on the drop at the needle tip for electrospinning process. If the conductivity of the solution is not sufficient, a jet cannot form, or a homogeneous fiber cannot be produced as the polymer liquid will not be fully stretched [ 74 – 75 ]. Salts or surfactants can be added to increase the conductivity [ 76 – 78 ].…”

Section: Reviewmentioning

confidence: 99%

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Electrospun nanofibers: building blocks for the repair of bone tissue

Serim,

Amasya,

Eren-Böncü

et al. 2024

Beilstein J. Nanotechnol.

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Bone, one of the hardest structures of the body, is the basic constituent of the skeletal system, which gives the shape to the body, provides mechanical support for muscles and soft tissues, and provides movement. Even if there is no damage, bone remodeling is a permanent process to preserve and renew the structural, biochemical, and biomechanical integrity of bone tissue. Apart from the remodeling, bone healing is the highly complicated process of repairing deficiencies of bone tissue by the harmonious operation of osteoblasts, osteocytes, osteoclasts, and bone lining cells. Various materials can be used to both trigger the bone healing process and to provide mechanical support to damaged bone. Nanofiber scaffolds are at the forefront of these types of systems because of their extremely large surface area-to-volume ratio, small pore size, and high porosity. Nanofibers are known to be highly functional systems with the ability to mimic the structure and function of the natural bone matrix, facilitating osteogenesis for cell proliferation and bone regeneration. Electrospinning is an easy and fast method to produce non-woven structures consisting of continuous ultrafine fibers with diameters ranging from micrometers down to nanometers. The simplicity and cost-effectiveness of the electrospinning technique, its ability to use a wide variety of synthetic, natural, and mixed polymers, and the formation of highly porous and continuous fibers are the remarkable features of this method. The importance of nanofiber-based scaffolds in bone tissue regeneration is increasing because of suitable pore size, high porosity, osteoinduction, induction of bone growth with osteoconduction, adaptability to the target area, biodegradation, and appropriate mechanical properties, which are among the main parameters that are important in the design of polymeric bone grafts. The aim of this review is to cast light on the increasing use of nanofiber-based scaffolds in bone tissue regeneration and give an insight about bone regeneration, production techniques of the electrospun nanofibers, and varying formulation parameters in order to reach different drug delivery goals. This review also provides an extensive market research of electrospun nanofibers and an overview on scientific research and patents in the field.

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Section: Reviewmentioning

confidence: 99%

“…The dielectric constant of a polymer liquid mainly depends on the solvent used. For the electrospinning process, the dielectric constant must be high enough [ 74 – 75 ]. With an increase in dielectric constant fewer beads and smaller fiber diameters are formed [ 80 ].…”

Section: Reviewmentioning

confidence: 99%

Electrospun nanofibers: building blocks for the repair of bone tissue

Serim,

Amasya,

Eren-Böncü

et al. 2024

Beilstein J. Nanotechnol.

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Surfactant interactions and solvent phase solubility modulate small molecule release from emulsion electrospun fibers

2021

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Emulsion electrospinning provides a tunable system for the development of porous scaffolds for controlled, localized drug delivery in tissue engineering applications. This study aimed to elucidate the role of model drug interactions with emulsion chemistry on loading and release rates from fibers with controlled fiber diameter and fiber volume fraction. Nile Red and Rhodamine B were used as model drugs and encapsulation efficiency and release rates were determined from poly(caprolactone) (PCL) electrospun fibers spun either with no surfactant (Span 80), surfactant, or water‐in‐oil emulsions. Drug loading efficiency and release rates were modulated by both surfactant and aqueous internal phase in the emulsions as a function of drug molecule hydrophobicity. Overall, these results demonstrate the role of intermolecular interactions and drug phase solubility on the release from emulsion electrospun fibers and highlight the need to independently control these parameters when designing fibers for use as tunable drug delivery systems.

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Effects of solvent on structures and properties of electrospun poly(ethylene oxide) nanofibers

Song

Chiang

Chu

et al. 2017

J of Applied Polymer Sci

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Poly(ethylene oxide) (PEO) nanofibers were prepared by electrospinning PEO solution with a mixed solvent of ethanol and deionized water. The results show that the mixed solvent system has noteworthy influences on structures and properties of electrospun PEO nanofibers, including molecular chain orientation, crystallinity degree, surface morphology, fiber diameter, diameter distribution, spinnability, and productivity. With increasing ethanol content in the mixed solvent, wrinkly morphologies appear on the surface of PEO nanofibers due to a high evaporation rate of ethanol during electrospinning process. The dielectric constant, dipole moment, conductivity, density, boiling point, and solubility parameter of the mixed solvent become lower with the ethanol content increasing. Besides, the hydrogen-bonding interactions between PEO and solvents become weaker. As a result, PEO nanofibers with larger diameters, lower molecular chain orientation, and crystallinity degree are obtained.

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Electrospinning of poly(butylene-carbonate):Effect of Solvents on the Properties of the Nanofibers Film

Cited by 29 publications

References 22 publications

Electrospun nanofibers: building blocks for the repair of bone tissue

Electrospun nanofibers: building blocks for the repair of bone tissue

Surfactant interactions and solvent phase solubility modulate small molecule release from emulsion electrospun fibers

Effects of solvent on structures and properties of electrospun poly(ethylene oxide) nanofibers

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