Electrophysiology, Pacing, and Devices

Stephenson, Elizabeth A.; Davis, Andrew M.

doi:10.1016/b978-0-7020-3064-2.00022-9

Cited by 1 publication

(1 citation statement)

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“…In clinical practice, first-degree AV block is common. It is characterized as a PR interval greater than 200 milliseconds (Stephenson et al 2010).…”

Section: Introductionmentioning

confidence: 99%

Characterization of rheumatic heart disease from electrocardiogram recordings

et al. 2023

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Objective: Rheumatic Heart Disease is one of the highly prevalent heart diseases in developing countries that can affect the pericardium, myocardium, or endocardium. Rheumatic endocarditis is a common RHD variant that gradually deteriorates the normal function of the heart valves. RHD can be diagnosed using standard echocardiography or listened to as a heart murmur using a stethoscope. The electrocardiogram is critical in the study and identification of heart rhythms and abnormalities. The effectiveness of ECG to identify distinguishing signs of RHD, however, has not been adequately examined. This study addressed the use of ECG recordings for the characterization of problems of the heart in RHD patients. Approach: An extensive ECG dataset was collected from patients suffering from RHD and healthy control subjects. Bandpass filtering was used at the preprocessing stage. Each data was then standardized by removing its mean and dividing by its standard deviation. Delineation of the onsets and offsets of waves was automatically performed. PR interval, QRS duration, RR intervals, QT intervals, and QTc intervals were computed for each heartbeat. The median values of the temporal parameters were used to eliminate possible outliers due to missed ECG waves. The data were clustered in different age groups and sex. Another categorization was done based on the time duration since the first RHD diagnosis. Main Results: In 47.2% of the cases, a PR elongation was observed, and in 26.4% of the cases, the QRS duration was elongated. QTc was elongated in 44.3% of the cases. It was also observed that 62.2% of the cases had bradycardia. Significance: The end product of this research can lead to new medical devices and services that can screen RHD based on ECG, which could assist in the detection and diagnosis of the disease in low-resource settings and alleviate the burden of the disease.

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“…In clinical practice, first-degree AV block is common. It is characterized as a PR interval greater than 200 milliseconds (Stephenson et al 2010).…”

Section: Introductionmentioning

confidence: 99%