Electrophysiology-Based Closed Loop Optogenetic Brain Stimulation Devices: Recent Developments and Future Prospects

Kumari, Lekshmy Sudha; Kouzani, Abbas Z.

doi:10.1109/rbme.2022.3141369

Cited by 6 publications

(2 citation statements)

References 129 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Specifically, the software employed in such devices must process the data and control the actuator with a time resolution that allows to change the system at a frequency meaningful for the specific application. 28,44,45…”

Section: Feedback Controlmentioning

confidence: 99%

Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices

2023

View full text Add to dashboard Cite

show abstract

Section: Feedback Controlmentioning

confidence: 99%

Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices

2023

View full text Add to dashboard Cite

show abstract

“…Many neuropathological disorders such as epileptic seizures [9], Parkinson's disease [10], and sleep-related disturbances [11] are required to be carefully studied in order to discover possible pathways for diagnostic and treatment approaches. In recent years, bidirectional interaction between astrocytic network and neuronal activity have been determined in the area of computational neuroscience.…”

Section: Related Workmentioning

confidence: 99%

A Digital Realization of Neuroglial Interaction Model and Its Network Structure

Seyedbarhagh

Ahmadi

2022

IEEE Access

View full text Add to dashboard Cite

Astrocyte cells, the most existing abundant cells in central nervous system, play an essential role in modulating the neuronal activities, information processing, and regulating the synaptic plasticity through calcium (Ca2+) fluctuations of ions hemostasis by using a feedback mechanism. The pathophysiological and hypersynchronous neuronal activity can lead to the epileptic seizures, which is known as one of the neurodegenerative disorders in the field of neuroscience. This paper presents a modified neuron-astrocyte interaction (tripartite synapse) model based on leaky and integrate fire neuron and the astrocyte-synapse models using an area-efficient hardware approach called stochastic computing paradigm. The proposed model is synthesized physically on field-programmable gate array as a proof of concept. The implementation results of the presented model can mimic the bidirectional communication in biological minimal network of pre-postsynaptic and Ca2+-based model for astrocyte with considerably lower hardware cost. The influence of astrocytes on neural network behavioral has been investigated by providing a proper feedback mechanism and considering the role of gap junction coupling and the various coefficients on desynchronizing the impaired synchronization of the coupled neurons.INDEX TERMS Astrocytes, Desynchronization, Field programmable gate array (FPGA), Neural-Glial interaction.

show abstract

An enhanced analysis of non-invasive human brain stimulation prediction for stroke patients using closed loop control scheme

Pothukuchi,

Memon,

Mallikarjunaradhya

et al. 2023

2023 Second International Conference on Smart Technologies for Smart Nation (SmartTechCon)

View full text Add to dashboard Cite

Electrophysiology-Based Closed Loop Optogenetic Brain Stimulation Devices: Recent Developments and Future Prospects

Cited by 6 publications

References 129 publications

Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices

Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices

A Digital Realization of Neuroglial Interaction Model and Its Network Structure

An enhanced analysis of non-invasive human brain stimulation prediction for stroke patients using closed loop control scheme

Contact Info

Product

Resources

About