Electrophysiological effects of methoxyflurane (Penthrane) on frog gastric mucosa

Tn, Mackrell; Schwartz, Mark R.

doi:10.1152/ajplegacy.1969.216.3.572

Cited by 3 publications

(1 citation statement)

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“…They found that the maximum acid output in rats anesthetized with halothane was less than half that for urethane anesthesia. Mackrell and Schwartz (22) reported that halothane (3-5% gassed for 30 min) produced a dose-dependent decrease in hydrogen ion secretion in the isolated gastric mucosa of frogs. Recently, Christensen and Skovsted (10) in vestigated the effect of halothane anesthesia on gastric juice volume and pH in 7 patients who underwent nonabdominal procedures.…”

Section: Discussionmentioning

confidence: 99%

Hydrochloric Acid and Cyclic 3’.5’-Adenosine Monophosphate Content of Rodent Gastric Juice after Halothane Administration

Geumei¹,

Danhof²

1978

Pharmacology

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Pulmonary aspiration of gastric contents during general anesthesia has always been a serious problem. Morbidity and mortality depend on the volume and acidity of the aspirated material. The anesthetic agent itself might affect gastric acid secretion. The effect of halothane (5, 10 and 20 mg/kg intravenously) on HCl secretion and cAMP content of gastric juice in pyloric and cardiac ligated male Sprague-Dawley rats was investigated. Compared with the control group, halothane significantly increased both HCl secretion and cAMP content of gastric juice, but to a lesser degree at the higher doses (p < 0.05).

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Section: Discussionmentioning

confidence: 99%

Hydrochloric Acid and Cyclic 3’.5’-Adenosine Monophosphate Content of Rodent Gastric Juice after Halothane Administration

Geumei¹,

Danhof²

1978

Pharmacology

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The Action of Inhalation Anesthetics on the Gastrointestinal Tract

Bennet¹,

Bass²

1972

Modern Inhalation Anesthetics

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Anomalous potential response and (Na+ + K+)-ATPase in in vitro frog gastric mucosa

Schwartz

Chu

Carrasquer

et al. 1981

Biochimica et Biophysica Acta (BBA) - Biomembranes

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Electrophysiological effects of methoxyflurane (Penthrane) on frog gastric mucosa

Cited by 3 publications

References 0 publications

Hydrochloric Acid and Cyclic 3’.5’-Adenosine Monophosphate Content of Rodent Gastric Juice after Halothane Administration

Hydrochloric Acid and Cyclic 3’.5’-Adenosine Monophosphate Content of Rodent Gastric Juice after Halothane Administration

The Action of Inhalation Anesthetics on the Gastrointestinal Tract

Anomalous potential response and (Na+ + K+)-ATPase in in vitro frog gastric mucosa

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Electrophysiological effects of methoxyflurane (Penthrane) on frog gastric mucosa

Cited by 3 publications

References 0 publications

Hydrochloric Acid and Cyclic 3&rsquo;.5&rsquo;-Adenosine Monophosphate Content of Rodent Gastric Juice after Halothane Administration

Hydrochloric Acid and Cyclic 3&rsquo;.5&rsquo;-Adenosine Monophosphate Content of Rodent Gastric Juice after Halothane Administration

The Action of Inhalation Anesthetics on the Gastrointestinal Tract

Anomalous potential response and (Na+ + K+)-ATPase in in vitro frog gastric mucosa

Contact Info

Product

Resources

About

Hydrochloric Acid and Cyclic 3’.5’-Adenosine Monophosphate Content of Rodent Gastric Juice after Halothane Administration

Hydrochloric Acid and Cyclic 3’.5’-Adenosine Monophosphate Content of Rodent Gastric Juice after Halothane Administration