Electrophoretic Patterns of Parotid Fluid Proteins from Caries-Resistant and Caries-Susceptible Individuals

Abstract

Parotid saliva samples from caries-resistant and caries-rampant individuals were electrophoresed on polyacrylamide gel slabs. The parotid saliva of the caries-rampant group showed a significantly higher level of anodemigrating proteins, predominantly isoamylases, and a significantly lower level of cathode-migrating proteins than that of the caries-resistant group in both paraffin-stimulated and sour lemon-stimulated salivary flows.

Selective effects of histidine‐rich polypeptides on the aggregation and viability of Streptococcus mutans and Streptococcus sanguis

“…Although the HRPs did not inhibit the growth of S. sanguis G9B, HRPs 1-2 significantly enhanced the growth of this organism. This observation tnay explain the finding of Balekjian et al (2), who reported a caries resistance correladon with parotid fiuid cadonic protein. The electrophoretic tnigration of some of the proteins in that study suggests a possible correlation with HRP 1.…”

Health benefits of saliva: a review

“…Mandel et al 62 found no difference in parotid saliva proteins between caries-resistant and caries-active adults. Balekjian et al 63 found that a caries-rampant group exhibited a significant reduction in the proportion of basic proteins and a significant increase in amylase compared to a caries-resistant group. Conversely, Mandel and Bennick found no differences in concentrations of the acidic PRPs between cariesfree and caries-susceptible subjects.…”

Salivary Proteins and Effects on Dental Caries: Review

“…Mandel ve ark., çürüklü ve çürüksüz erişkin-lerin parotid tükürüğündeki protein düzeylerinde herhangi bir fark olmadığını bildirirken; 20 Balekjian ve ark., çürüksüz bireylerle kıyaslandığında, yaygın çürükleri olan grupta tükürük protein seviyesinde önemli bir azalma ve amilaz miktarında önemli derecede artma gözlemlemişlerdir. 21 …”