Abstract-In this letter, we analyze the benefit of digital compensation of fiber nonlinearity, where the digital signal processing is divided between the transmitter and the receiver. The application of the Gaussian noise model indicates that, where there are two or more spans, it is always beneficial to split the nonlinearity compensation. The theory is verified via numerical simulations, investigating the transmission of a single-channel 50-GBd polarization division multiplexed 4-and 256-ary quadrature amplitude modulation signals over 100-km standard singlemode fiber spans, using lumped amplification. It is shown, theoretically, that the signal-to-noise ratio gain for long distances and high bandwidth transmission is 1.5 dB versus transmitteror receiver-based nonlinearity compensation.