“…The synthesis of linear aldehydes is of high interest for industrial purposes, and very high regioselectivities (l/b > 99:1) have been achieved from terminal alkenes with rhodium catalysts using bulky bisphosphine (e.g., Bisbi [2] and Naphos [3]) and bisphosphite (e.g., Biphephos [4]) ligands. However, the selective formation of linear aldehydes is much more challenging when starting from internal alkene as, in this case, preliminary isomerization of the C=C bond is necessary to bring it to the terminal position before performing the hydroformylation process itself.…”