Electron Microscopy

Swerdlow, Max

doi:10.1021/ac60085a007

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1955

1960

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Cited by 10 publications

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“…Even though a comprehensive li teratme of collagen exists [1]/ additional data and fundamen tal concepts concerning the morphogensis and basic structure are still being sought [2]. R ecently, the structure of collagen has been amply reviewed and evalu ated [3,4,5, 5a].…”

Section: Introductionmentioning

confidence: 99%

Collagen pores determined by electron microscopy

Swerdlow¹,

Stromberg²

1955

J. RES. NATL. BUR. STAN.

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The existence and morphology of pores of the order of 150 A, in radius, within collagen fibrils is delineated. Structural features of collagen from air-dried kangaroo tail tendon, impreO"nated with mercury at a p ress ure of 10,800 psi., are compared with those of fibril s not. exposed to mercury. A helical configuration of sub fibrillar elements is suggested by t~e electron microgaphs of individual fibrils. The possible use of mercury under hydrostattc pressure as a technique in staini ng and preserving the structur e of biological materials for electron microscopy is advanced. These findings constitute a .visual c

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Section: Introductionmentioning

confidence: 99%