Electron microscopic study of 'Rushton' hyaline bodies in cyst linings

Allison, R.T.

doi:10.1038/sj.bdj.4803243

Cited by 12 publications

(14 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Rushton hyaline bodies. The presence of Rushton hyaline bodies is a feature unique to some odontogenic cysts and their frequency in cysts varies from 2.6% to 9.5% . Rushton hyaline bodies usually appear either within the epithelial lining or the cyst lumen (Fig.…”

Section: Disease Relationshipsmentioning

confidence: 99%

Interaction between endodontics and periodontics

Rotstein¹

2017

Periodontology 2000

View full text Add to dashboard Cite

Endodontic-periodontal lesions present challenges to the clinician regarding diagnosis, treatment planning and prognosis. Etiologic factors, such as bacteria and viruses, as well as contributing factors, such as trauma, root resorptions, perforations, cracks and dental malformations, play an important role in the development and progression of such lesions. Treatment and prognosis of endodontic-periodontal lesions vary, depending on the etiology, pathogenesis and correct diagnosis of each specific condition. This chapter will appraise the interrelationship between endodontic and periodontal lesions and provide biological and clinical evidence for diagnosis, prognosis and decision-making in the treatment of these conditions.

show abstract

Section: Disease Relationshipsmentioning

confidence: 99%

Interaction between endodontics and periodontics

Rotstein¹

2017

Periodontology 2000

View full text Add to dashboard Cite

show abstract

“…Their frequency varies from 2.6% to 9.5% (140). They have a variety of morphological forms, including linear (straight or curved), irregular, rounded, and polycyclic structures, or they may appear granular (29,140). 6).…”

Section: Rushton Hyaline Bodiesmentioning

confidence: 99%

The endo‐perio lesion: a critical appraisal of the disease condition

Rotstein¹,

Simon²

2006

Endodontic Topics

View full text Add to dashboard Cite

Endodontic–periodontal lesions present challenges to the clinician as far as diagnosis and prognosis of the involved teeth are concerned. Etiologic factors such as bacteria, fungi, and viruses as well as various contributing factors such as trauma, root resorptions, perforations, and dental malformations play an important role in the development and progression of such lesions. Treatment and prognosis of endodontic–periodontal diseases vary and depend on the cause and the correct diagnosis of each specific condition. This article will appraise the interrelationship between endodontic and periodontal diseases and provide biological and clinical evidence of significance for diagnosis, prognosis, and decision‐making in the treatment of these conditions.

show abstract

“…They are negative with von Kossa stain for calcium and the periodic acid‐Schiff reaction for mucopolysaccharides (2). Based on the results of histochemical examinations and electron microscopic observations, certain substances, such as keratins produced by the odontogenic epithelium, may play a role in HB formation (2, 3, 6–8). As histochemical reactions of HBs are similar to those of dental cuticles and different from those of epithelial keratins, particular secretory proteins other than keratins have also been considered (4, 5).…”

Section: Introductionmentioning

confidence: 99%

Ectopic production of hair keratin constitutes Rushton’s hyaline bodies in association with hematogenous deposits

Sakamoto

Khanom

Hamagaki

et al. 2012

J Oral Pathology Medicine

View full text Add to dashboard Cite

A Rushton's hyaline body (HB) is a concretion occasionally found in odontogenic cysts. Unspecified substances produced by the lining epithelium or derived from blood components have been suggested as possible causes of HB formation, but the origin of HBs is still elusive. This study aimed to clarify the origin of HBs. Ten specimens with HBs were obtained from 400 odontogenic cysts. HBs were stained by orcein and Congo red. Immunohistochemical examination revealed that HBs were positive for hair keratin and keratin 17. Hair keratin was concentrated in HBs, and cells with hair keratin expression were hardly seen, while cells with keratin 17 expression were observed near HBs. HBs were also positive for hemoglobin alpha chain. The presence of hair keratin in HBs was confirmed by Western blot analysis. The present study suggests that HBs are formed as a consequence of two independent events: unusual alteration of epithelial differentiation so as to provide hair keratin, and hemorrhage so as to provide erythrocytic substances. Although the ectopic production of hair keratin appears more essential, our results reconcile the long-standing debate between two theories, the keratin theory versus the hematogenous theory, concluding that both substances are required for the genesis of HBs, and also suggesting that they might be novel non-pathological amyloidogenic proteins.

show abstract

Electron microscopic study of 'Rushton' hyaline bodies in cyst linings

Cited by 12 publications

References 0 publications

Interaction between endodontics and periodontics

Interaction between endodontics and periodontics

The endo‐perio lesion: a critical appraisal of the disease condition

Ectopic production of hair keratin constitutes Rushton’s hyaline bodies in association with hematogenous deposits

Contact Info

Product

Resources

About