Electron Microscopic Studies on the Development of the Human Lens

Surgical outcomes of phototherapeutic keratectomy on Epithelial basement membrane dystrophy, and the characterisation of Bowman's Layer

“…The surface ectoderm (the outermost of the three primitive germ layers of the embryo) invaginates into the optic cup and then after producing the lens vesicle, the surface layers separate and form the epithelium and later the epithelium secretes the basement membrane [31]. From the neural crest (a band of neuroectodermal cells) the stroma is later composed from collagen fibrils between the lens and the epithelium.…”

The lens capsule and zonulae

“…The initiation of this process is caused by the apposition of the optic cup onto the ectoderm. The lens capsule can first be detected in at about 40 days of gestation (11 mm stage) (Lerche & Wulle 1969). The capsule production starts at the point where the lens detaches itself from the surface ectoderm.…”

Accumulation and distribution of sulfated materials in the maturing mouse lens capsule

“…During this period, the basal 1983). Autoradiographic studies have demonstrated that lamina of the lens vesicle thickens (Cohen, 1961; Lerche newly synthesized collagen is added by accretion to the and Wuulle, 1969;Silver and Wakely, 1974) and accu-previously secreted layers with little or no interminmulates collagen (Silver and Wakely, 1974; gling between the layers or turnover of capsular collaal., 19831, forming a precursor of the adult lens capsule. gen (Young and Ocumpaugh, 1966;Rafferty and It has been suggested that the lens capsule is similar in Goossens, 1978).…”