“…However, still some problems have remained such as the extrusion mode of the islet cell granules especially of B-cells, which was postulated by some investigators to be diacrine (FUJITA and MATSUNO, 1967;KOHAMA, 1968) or KUROSUMI'S (1961) Type V, whereas by others it is thought to be eruptocrine (LACY, 1962;BJORKMAN et al, 1963;WILLIAMS and ENSINCK, 1966) or a Type IV mechanism (KUROSUMI, 1961).…”