An expression for the conductance of interacting electrons in the diffusive regime as a function of the ensemble averaged persistent current and the compressibility of the system is presented. This expression involves only ground-state properties of the system. The different dependencies of the conductance and persistent current on the electron-electron interaction strength becomes apparent. The conductance and persistent current of a small system of interacting electrons are calculated numerically and their variation with the strength of the interaction is compared. It is found that while the persistent current is enhanced by interactions, the conductance is suppressed.PACS numbers: 71.55. Jv,71.27.+a,73.20.Dx There has been much recent interest in the physics of interacting electrons in disordered systems [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]. Part of this attention is motivated by the large amplitudes of persistent currents observed in mesoscopic metallic rings [20,21]. These values are larger by up to two orders of magnitude than theoretical predictions based on the single electron picture using the value of the mean free path as measured by transport experiments. Another motivation has to do with the rich physics contained therein. The metal-insulator transition can be triggered by two different physical mechanisms: electron-electron (e-e) interactions (generally referred to as the Mott-Hubbard transition) and disorder (known as the Anderson transition). Although much effort has been devoted to the investigation of the interplay between the two, the problem of metal-insulator transition in the presence of disorder and interactions is not yet completely settled [22,23].Theoretically, it has been established that due to e-e interactions the amplitude of the persistent current (at zero-temperature) may be enhanced compared to its noninteracting value. The precise nature of this interaction induced modification depends on the model used and on the specific domains in parameter space. For spinless electrons in one-dimensional (1D) continuum models the amplitude can reach its disorder-free value for strong interactions [8]. On the other hand for spinless electrons in 1D lattice models a negligible enhancement of the amplitude occurs and that happens only for weak interactions in the localized regime [9,12,14]. When spin is taken into account, a sizable enhancement of the amplitude is found [17,18]. Large enhancements occur also for 2D and 3D spinless electrons in lattice models for weak and medium ranges of interaction strengths [16,19].Thus one may conclude that it is conceivable that significant enhancement of persistent currents may result in calculations for realistic 3D lattice models which take spin into account. Nevertheless, there still remain several important questions which have not yet been fully answered. The first, and perhaps the most interesting one from a general point of view, is why does e-e interaction play such an important role in the determination of the per...