Electron beam switched trapping and release of nanoparticles on nanopore array

Electron-beam-controlled reversible concentration of nanoparticles on a nanopore

“…In this article, we report on a preliminary control method to concentrate a liquid sample in a micrometer-scale region and to deliver the sample to a vacuum for analysis; the method has the potential to contribute to not only micromanipulation 20) for lab-on-a-chip devices but also to accelerate local crystallization and ionization for distribution analysis of intact proteins using LILBID-MS. The concentration and delivery flow to the vacuum were induced by a pressure difference on a nanopore.…”

“…The locally induced nanoflow for particle clustering and repulsion force could be applied to biomanipulations for the lateral transport of nanoparticles on a nanopore array. 20) Acknowledgments This work was partly supported by the Precise Measurement Technology Promotion Foundation and JSPS KAKENHI Grant Number 15H05511.…”