Electron beam/ γ -ray irradiation synthesis of gold nanoparticles and investigation of antioxidant activity

Abstract

Colloidal solutions of 1 mM gold nanoparticles (AuNPs) were synthesized by γ-ray Co-60 and electron beam irradiation using 1% water soluble chitosan (WSC) with different molecular weight (Mw) as stabilizer. The AuNPs size measured from TEM images was of 7.1 and 15.1 nm for electron beam and γ-ray Co-60, respectively. The AuNPs sizes of 9.8, 15.1 and 22.4 nm stabilized by different WSC Mw of 155 × 10 3 , 78 × 10 3 and 29 × 10 3 g mol −1 , respectively, were also synthesized by γ-ray Co-60 irradiation. Antioxidant activity of AuNPs with different size from 7.1 to 20.0 nm was investigated using free radical 2,2′-azino-bis (3-ethylbenzothiazoline-6sulphonic acid) (ABTS •+ ). Results indicated that the smaller size of AuNPs exhibited higher antioxidant activity. In particular, the antioxidant efficiency was of nearly 100, 75, 65, 52 and 30% for 7.1, 9.8, 15.1, 20.0 nm AuNPs and WSC 0.1%, respectively, at the same reaction time of 270 min. Thus, due to the compatibility of WSC and the unique property of AuNPs, the pure colloidal AuNPs/WSC solutions synthesized by irradiation method can be potentially applied in biomedicine, cosmetics and in other fields as well.

Synthesis of Platinum Nanoparticles by Gamma Co-60 Ray Irradiation Method Using Chitosan as Stabilizer

“…Furthermore, the size of the synthesized PtNPs (1.4-1.6 nm) was also smaller than that of the PtNPs (3.4 nm) that were synthesized by the chemical method using NaBH 4 as a reducing agent with the same initial concentration of 1 mM Pt 4+ and 1% CTS as a stabilizer [5]. Moreover, the study on the synthesis of Ag and Au nanoparticles by the gamma Co-60 ray irradiation method using CTS as a stabilizer revealed that the size of Ag and Au nanoparticles was 4.6 and 9.8 nm for 1 mM Ag + and Au 3+ ions, respectively [16,20]. us, it is obvious that the size of PtNPs synthesized by the gamma Co-60 ray irradiation method is smaller than that of Ag and Au nanoparticles at the same initial concentration of metal ions.…”

An Overview of the Synthesis of Gold Nanoparticles Using Radiation Technologies

“…As for high-energy accelerators, the energy is around 5–10 MeV with energies up to 100 kW. For instance, the expected penetration of a high energy accelerator of 10 MeV is around ~38 mm, depending on the density of the material [ 94 , 99 ]. The technology holds high throughput and offers as an advantage a recognized operational safety and power [ 94 , 99 ].…”

Amperometric detection of carbohydrates based on the glassy carbon electrode modified with gold nano-flake layer

“…Thus, high concentration of HAuCl 4 was likely to give equal possibility for all gold clusters to grow into nano-flakes and only gold nano-flakes is able to maintain its activity in PAD for carbohydrates. In our previous study, the antioxidant efficiency of gold nano-particles decreased with its size [15] as the explanation for the stability of the gold nano-flakes in PAD condition. It should be noted that the inclination of nano-flakes in Fig.…”