Take-Home Messages• A theory of Chee for the 47-ccntury old Traditional Chinese Medicine (TCM) has been formulated by this author in an approach similar to that of Julius Stratton for electromagnetic theory in 1941. • The theory of Chee and its validation and experimentation are transforming TCM into Scientific TCM (STCM).• Targeted biological and medical applications are on solving major health problems that modern science and technology are unable-or too costly-to solve, with initial focuses on mental illnesses, inflammation, allergy, and infectious diseases.