Electromagnetic fields for the treatment of osteoarthritis

Hulme, Jennifer; Welch, Vivian; Bie, Rob de; Judd, Maria; Tugwell, Peter

doi:10.1002/14651858.cd003523

Cited by 80 publications

(55 citation statements)

References 10 publications

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“…Recent studies in humans suggest chronic pain as a potential application field for magnetic therapy as a non-contact, non-invasive and cheap physiotherapeutic method: in osteoarthritis [Hulme et al, 2002], spine disorders [Linovitz et al, 2002], abdominal and genital pain [Holcomb et al, 2000], chronic pelvic pain [Brown et al, 2002], knee pain , fibromyalgia [Alfano et al, 2001], myofascial pain syndrome [Smania et al, 2003], and diabetic neuropathic pain [Weintraub et al, 2009].…”

Section: Introductionmentioning

confidence: 99%

Lateral gradients significantly enhance static magnetic field‐induced inhibition of pain responses in mice—a double blind experimental study

Kiss

Gyires

Kellermayer

et al. 2013

Bioelectromagnetics

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Recent research demonstrated that exposure of mice to both inhomogeneous (3–477 mT) and homogeneous (145 mT) static magnetic fields (SMF) generated an analgesic effect toward visceral pain elicited by the intraperitoneal injection of 0.6% acetic acid. In the present work, we investigated behavioral responses such as writhing, entry avoidance, and site preference with the help of a specially designed cage that partially protruded into either the homogeneous (ho) or inhomogeneous (inh) SMF. Aversive effects, cognitive recognition of analgesia, and social behavior governed mice in their free locomotion between SMF and sham sides. The inhibition of pain response (I) for the 0–5, 6–20, and 21–30 min periods following the challenge was calculated by the formula I = 100 (1 − x/y) in %, where x and y represent the number of writhings in the SMF and sham sides, respectively. In accordance with previous measurements, an analgesic effect was induced in exposed mice (Iho = 64%, P < 0.0002 and Iinh = 62%, P < 0.002). No significant difference was found in the site preference (SMFho, inh vs. sham) indicating that SMF is neither aversive nor favorable. Comparison of writhings observed in the sham versus SMF side of the cage revealed that SMF exposure resulted in significantly fewer writhings than sham (Iho = 64%, P < 0.004 and Iinh = 81%, P < 0.03). Deeper statistical analysis clarified that the lateral SMF gradient between SMF and sham sides could be responsible for most of the analgesic effect (Iho = 91%, P < 0.02 and Iinh = 54%, P < 0.02). Bioelectromagnetics 34:385–396, 2013. © 2012 Wiley Periodicals, Inc.

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Section: Introductionmentioning

confidence: 99%

Lateral gradients significantly enhance static magnetic field‐induced inhibition of pain responses in mice—a double blind experimental study

Kiss

Gyires

Kellermayer

et al. 2013

Bioelectromagnetics

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“…36,37 Since then, PEMFs have been applied increasingly, including their use in the treatment of osteoarthritis and (non-united) fractures. 188,353 Th ey are designed as a portable PEMF generator, which consists of electromagnetic fi elds with an on-off eff ect of pulsing. Th is produces athermal eff ects that suppress infl ammation, promote tissue healing, and relieve pain.…”

Section: Introductionmentioning

confidence: 99%

“…PEMF as a solitary treatment for osteoarthritis of the knee has been repeatedly investigated, with confl icting results. 131,188,278,385,400 Although the eff ect of PEMFs on osteoarthritis of the knee seems equivocal, their value in the additional treatment of other bony and cartilaginous pathologies is promising. PEMFs have been proven as a successful method in fracture healing, especially in the case of nonunion.…”

Section: Introductionmentioning

confidence: 99%

Treatment of osteochondral defects of the talus

Bergen

Leeuw

Dijk

2008

Revue de Chirurgie Orthopédique et Réparatrice de l'Appareil Mo

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“…They concluded that PEMF can potentially modify the complex pathological processes that occur in tissue damaged by OA. Hulme et al reviewed studies involving the use of PEMF in OA treatment [10]. They found small to moderate but significant results in knee OA patients and more limited but positive results in cervical spine OA patients.…”

Section: Pulsed Electromagnetic Fieldsmentioning

confidence: 99%

Efficacy of selected complementary and alternative medicine interventions for chronic pain

Tan

Craine

Bair³

et al. 2007

JRRD

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Abstract-Complementary and alternative medicine (CAM)is a group of diverse medical and healthcare systems, therapies, and products that are not presently considered part of conventional medicine. This article provides an up-to-date review of the efficacy of selected CAM modalities in the management of chronic pain. Findings are presented according to the classification system developed by the National Institutes of Health National Center for Complementary and Alternative Medicine (formerly Office of Alternative Medicine) and are grouped into four domains: biologically based medicine, energy medicine, manipulative and body-based medicine, and mind-body medicine. Homeopathy and acupuncture are discussed separately as "whole or professionalized CAM practices." Based on the guidelines of the Clinical Psychology Division of the American Psychological Association, findings indicate that some CAM modalities have a solid track record of efficacy, whereas others are promising but require additional research. The article concludes with recommendations to pain practitioners.

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Electromagnetic fields for the treatment of osteoarthritis

Cited by 80 publications

References 10 publications

Lateral gradients significantly enhance static magnetic field‐induced inhibition of pain responses in mice—a double blind experimental study

Lateral gradients significantly enhance static magnetic field‐induced inhibition of pain responses in mice—a double blind experimental study

Treatment of osteochondral defects of the talus

Efficacy of selected complementary and alternative medicine interventions for chronic pain

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