Electrolyte-gated transistors for synaptic electronics, neuromorphic computing, and adaptable biointerfacing

Abstract

DOI to the publisher's website.• The final author version and the galley proof are versions of the publication after peer review.• The final published version features the final layout of the paper including the volume, issue and page numbers. Link to publication General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal.If the publication is distributed under the terms of Article 25fa of the Dutch Copyright Act, indicated by the "Taverne" license above, please follow below link for the End User Agreement:

Organic materials and devices for brain-inspired computing: From artificial implementation to biophysical realism

“…68 Among various device concepts, electrochemical devices based on organic mixed-conductors have recently emerged for brain-inspired computing (organic electrochemical transistors or OECTs, and electrochemical organic neuromorphic devices or ENODes). 27,33 Mapping synaptic weights is facile in electrochemical organic neuromorphic devices, as almost linear tuning of the device resistance is achieved by proper programming conditions and by the use of a third, gate terminal that decouples the read and write actions. 45,67 In situ polymerization of the active organic material during the device operation even allows for an evolvable type of organic electrochemical transistor that emulates the formation of new synapses in biological networks (synaptogenesis).…”

“…These models are the main source of inspiration for the realization of devices for brainlike computing. We also review the latest advancements in organic neuromorphic devices for the implementation of hardware and hybrid intelligent agents (for more detailed reading about organic neuromorphic electronics, please refer to the topical reviews 27,33,34 ). A comparison between biophysical and artificial models of the nervous system is provided, indicating the gap between them in several aspects of neural processing.…”

Organic Bioelectronics: Using Highly Conjugated Polymers to Interface with Biomolecules, Cells, and Tissues in the Human Body

“…We focus exclusively on interfaces that use highly conjugated polymers to interface an aspect of human physiology, where the polymer's primary proposed use relies on its electronic properties. For example, we do not discuss organic small molecule devices, conjugated polymer nanoparticles for imaging or optical biosensing, [ 3–5 ] biomimicking neuromorphic designs, [ 6–8 ] hydrogen‐bond mediated bioprotonics, [ 9–11 ] or polymers for nonelectronic/ionic driven drug delivery. [ 12 ] We also include a brief discussion of the origin of bioelectricity itself, as this is fundamental to the motivation and application of many organic bioelectronic interfaces.…”

Ion Coordination and Chelation in a Glycolated Polymer Semiconductor: Molecular Dynamics and X-Ray Fluorescence Study

“…1 The great interest in OECTs and, more broadly, in mixed transport is proportional to the variety of applications where these devices have disrupted the state-of-the-art: from bioelectronics 2,3 and healthcare (neural interfaces, chemical and biological sensors 4,5 ), to energy production 6 and storage, 7 to artificial synapses. 8,9 These applications exploit the similarity between OECT operation and the way our cells send and receive signals, opening facile integration with biological substrates.…”