Electrolyte changes and the electrocardiogram in diabetic acidosis

Electrocardiographic Alterations Produced by a Decrease in Plasma pH, Bicarbonate and Sodium as Compared with those Produced by an Increase in Potassium

“…1 ' 3 In many of these conditions, there occurs a coincident decrease in sodium, bicarbonate, and pH accompanied by variable disturbances in chloride, phosphate, and magnesium. 1 " 8 The effects of potassium, calcium, and magnesium on the electrocardiogram have been well defined experimentally.…”

“…The present experiments in normal dogs were undertaken (1) to define the electrocardiographic changes which occur as a result of disturbances of those ions known to be altered in clinical situations associated with hyperkalemia, and (2) to correlate these changes with those previously ascribed solely to potassium.…”

Three Cases of Acute Ketotic Diabetes Mellitus with Myocarditis: A Common Viral Origin?

“…Three of Cole's cases followed mumps, and others have confirmed this finding (Kremer, 1947;Melin and Ursing, 1958). Infection with encephalomyocardtis virus (Craighead and Stienke, 1961) and Coxsfackie group B4 virus (Coleman et al, 1973) have produced experimental diabetes in animals, and human diabetes is commoner in the colder months when viral infections are more prevalent (Adams, 1926;Gamble and Taylor, 1969).…”

“…In about half the cases there is disparity between the severity of the ketosis and the resultant E.C.G. abnormalities (Bellet and Dyer, 1937;Martin and Wertman, 1947;Henderson, 1953).…”