Electrolyte and hematological abnormalities in patients with advanced epithelial ovarian cancers treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) or neoadjuvant chemotherapy plus CRS/HIPEC

Díaz-Montes, Teresa; Vélez-Mejía, Carolina; Sittig, Michelle; MacDonald, Ryan; Gushchin, Vadim; Ducie, J.A.; Ryu, Hyung S.; Sardi, Armando

doi:10.1016/j.ygyno.2019.04.340

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“…Diaz-Montes and colleagues reported transient hypocalcemia to be present for a duration of 1 week in 41 patients who underwent cytoreductive surgery and HIPEC for gynecologic cancers. Spontaneous resolution of hypocalcemia was noted at 1-month follow-up [4]. Kapoor and colleagues reported asymptomatic hypocalcemia in 29 of 31 patients (94 %) after undergoing laparoscopic assisted HIPEC with cisplatin and mitomycin C for gastric cancers [5].…”

Section: Severe Hypocalcemia and Transient Hypoparathyroidism After Hmentioning

confidence: 96%

“…In the absence of these factors, only slight decreases in calcium levels within the normal range have been reported during surgical procedures [1]. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) causing asymptomatic hypocalcemia has only been reported in two previous studies [4,5]. The etiology is unclear.…”

Section: Severe Hypocalcemia and Transient Hypoparathyroidism After Hmentioning

confidence: 99%

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Severe Hypocalcemia and Transient Hypoparathyroidism After Hyperthermic Intraperitoneal Chemotherapy

et al. 2020

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Dear Editors,Hypocalcemia is not unusual in patients hospitalized for critical illness and has also been described after general surgery in addition to head and neck surgical procedures 1 2 3. Hypocalcemic events commonly occur in the setting of massive blood transfusion, albumin deficiency, vitamin D deficiency, and/or hypomagnesemia. In the absence of these factors, only slight decreases in calcium levels within the normal range have been reported during surgical procedures 1. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) causing asymptomatic hypocalcemia has only been reported in two previous studies 4 5. The etiology is unclear. We here report a patient who developed severe symptomatic hypocalcemia likely as a result of a profound inflammatory reaction with transient hypoparathyroidism after HIPEC.

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Section: Severe Hypocalcemia and Transient Hypoparathyroidism After Hmentioning

confidence: 96%

Section: Severe Hypocalcemia and Transient Hypoparathyroidism After Hmentioning

confidence: 99%

Severe Hypocalcemia and Transient Hypoparathyroidism After Hyperthermic Intraperitoneal Chemotherapy

et al. 2020

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Electrolyte and hematological abnormalities in patients with advanced epithelial ovarian cancers treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) or neoadjuvant chemotherapy plus CRS/HIPEC

Cited by 1 publication

References 0 publications

Severe Hypocalcemia and Transient Hypoparathyroidism After Hyperthermic Intraperitoneal Chemotherapy

Severe Hypocalcemia and Transient Hypoparathyroidism After Hyperthermic Intraperitoneal Chemotherapy

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