Abstract:It is known that the "race for the surface" determining the in vivo response is strictly connected to the physico-chemical properties of the material, especially at its surface. Accordingly, the study of surface roughness, charge and wettability is fundamental to predict the bio-response to the implant. In this work, streaming potential was chosen as a reliable method to quantify the solid surface charge of hydrothermally treated (HT) TiO2-anatase nano-crystalline coatings, grown on titanium substrates. The in… Show more
“…The value of x z = 2.5 nm at lower salt concentrations as determined in Fig. 6b was predicted also in [12, 13, 16]. Fig.…”
Section: Resultssupporting
confidence: 79%
“…Together with the choice for the most suitable surface modification technique, the evaluation of the physico-chemical properties of a biomaterial surface is compulsory for the proper design of body implants and to predict a priori the influence of the material properties on the events occurring at the bio-interface [ 12 , 13 ]. In fact, the surface properties are responsible for the interactions with the surrounding tissues and, influencing the “race for the surface” between cells and bacteria [ 14 ], affect the consequent acceptance of the implant.…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, in the next step, the zeta potential of self-assembled TiO 2 NTs on Ti surfaces was measured by streaming potential technique, when still adhered to the substrate [ 16 ]. Streaming potential represents a reliable method to evaluate the surface charge by determining the zeta potential ( ζ ) at the interface between the material and the fluid around [ 12 , 13 , 16 ]. Differently from electrophoresis and electroacoustic techniques, the streaming potential technique consists in the formation of an electric field as the electrolyte flows tangentially to a stationary charged solid surface, so that the zeta potential is calculated out of the generated streaming potential.…”
Surface charge is one of the most significant properties for the characterisation of a biomaterial, being a key parameter in the interaction of the body implant with the surrounding living tissues. The present study concerns the systematic assessment of the surface charge of electrochemically anodized TiO2 nanotubular surfaces, proposed as coating material for Ti body implants. Biologically relevant electrolytes (NaCl, PBS, cell medium) were chosen to simulate the physiological conditions. The measurements were accomplished as titration curves at low electrolytic concentration (10−3 M) and as single points at fixed pH but at various electrolytic concentrations (up to 0.1 M). The results showed that all the surfaces were negatively charged at physiological pH. However, the zeta potential values were dependent on the electrolytic conditions (electrolyte ion concentration, multivalence of the electrolyte ions, etc.) and on the surface characteristics (nanotubes top diameter, average porosity, exposed surface area, wettability, affinity to specific ions, etc.). Accordingly, various explanations were proposed to support the different experimental data among the surfaces. Theoretical model of electric double layer which takes into account the asymmetric finite size of ions in electrolyte and orientational ordering of water dipoles was modified according to our specific system in order to interpret the experimental data. Experimental results were in agreement with the theoretical predictions. Overall, our results contribute to enrich the state-of-art on the characterisation of nanostructured implant surfaces at the bio-interface, especially in case of topographically porous and rough surfaces.
“…The value of x z = 2.5 nm at lower salt concentrations as determined in Fig. 6b was predicted also in [12, 13, 16]. Fig.…”
Section: Resultssupporting
confidence: 79%
“…Together with the choice for the most suitable surface modification technique, the evaluation of the physico-chemical properties of a biomaterial surface is compulsory for the proper design of body implants and to predict a priori the influence of the material properties on the events occurring at the bio-interface [ 12 , 13 ]. In fact, the surface properties are responsible for the interactions with the surrounding tissues and, influencing the “race for the surface” between cells and bacteria [ 14 ], affect the consequent acceptance of the implant.…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, in the next step, the zeta potential of self-assembled TiO 2 NTs on Ti surfaces was measured by streaming potential technique, when still adhered to the substrate [ 16 ]. Streaming potential represents a reliable method to evaluate the surface charge by determining the zeta potential ( ζ ) at the interface between the material and the fluid around [ 12 , 13 , 16 ]. Differently from electrophoresis and electroacoustic techniques, the streaming potential technique consists in the formation of an electric field as the electrolyte flows tangentially to a stationary charged solid surface, so that the zeta potential is calculated out of the generated streaming potential.…”
Surface charge is one of the most significant properties for the characterisation of a biomaterial, being a key parameter in the interaction of the body implant with the surrounding living tissues. The present study concerns the systematic assessment of the surface charge of electrochemically anodized TiO2 nanotubular surfaces, proposed as coating material for Ti body implants. Biologically relevant electrolytes (NaCl, PBS, cell medium) were chosen to simulate the physiological conditions. The measurements were accomplished as titration curves at low electrolytic concentration (10−3 M) and as single points at fixed pH but at various electrolytic concentrations (up to 0.1 M). The results showed that all the surfaces were negatively charged at physiological pH. However, the zeta potential values were dependent on the electrolytic conditions (electrolyte ion concentration, multivalence of the electrolyte ions, etc.) and on the surface characteristics (nanotubes top diameter, average porosity, exposed surface area, wettability, affinity to specific ions, etc.). Accordingly, various explanations were proposed to support the different experimental data among the surfaces. Theoretical model of electric double layer which takes into account the asymmetric finite size of ions in electrolyte and orientational ordering of water dipoles was modified according to our specific system in order to interpret the experimental data. Experimental results were in agreement with the theoretical predictions. Overall, our results contribute to enrich the state-of-art on the characterisation of nanostructured implant surfaces at the bio-interface, especially in case of topographically porous and rough surfaces.
“…The value of x z = 2.5 nm at lower salt concentrations as determined in Fig. 6b was predicted also in [12,13,16]. The value of the surface charge density σ = −0.05 As/m 2 for Ti foil, which was estimated from the experimentally determined values of ζ potential (Fig.…”
Section: Effect Of the Electrolytic Concentration On The ζ Valuessupporting
confidence: 64%
“…Together with the choice for the most suitable surface modification technique, the evaluation of the physicochemical properties of a biomaterial surface is compulsory for the proper design of body implants and to predict a priori the influence of the material properties on the events occurring at the bio-interface [12,13]. In fact, the surface properties are responsible for the interactions with the surrounding tissues and, influencing the "race for the surface" between cells and bacteria [14], affect the consequent acceptance of the implant.…”
Surface charge is one of the most significant properties for the characterisation of a biomaterial, being a key parameter in the interaction of the body implant with the surrounding living tissues. The present study concerns the systematic assessment of the surface charge of electrochemically anodized TiO 2 nanotubular surfaces, proposed as coating material for Ti body implants. Biologically relevant electrolytes (NaCl, PBS, cell medium) were chosen to simulate the physiological conditions. The measurements were accomplished as titration curves at low electrolytic concentration (10 −3 M) and as single points at fixed pH but at various electrolytic concentrations (up to 0.1 M). The results showed that all the surfaces were negatively charged at physiological pH. However, the zeta potential values were dependent on the electrolytic conditions (electrolyte ion concentration, multivalence of the electrolyte ions, etc.) and on the surface characteristics (nanotubes top diameter, average porosity, exposed surface area, wettability, affinity to specific ions, etc.). Accordingly, various explanations were proposed to support the different experimental data among the surfaces. Theoretical model of electric double layer which takes into account the asymmetric finite size of ions in electrolyte and orientational ordering of water dipoles was modified according to our specific system in order to interpret the experimental data. Experimental results were in agreement with the theoretical predictions. Overall, our results contribute to enrich the state-of-art on the characterisation of nanostructured implant surfaces at the bio-interface, especially in case of topographically porous and rough surfaces.
19Al 2 O 3 films were coated on SUS304L stainless steel and fused silica substrates 20 using chemical solution deposition. Continuous pores with a diameter of 21 approximately 2 nm were observed through the measurement of the pore 22 J Mater Sci Ceramics Author Proof
52Zeta potential control is a method to suppress the 53 deposition of solid particles onto the surfaces of 54 parts. In this method, a film with the same zeta 55 potential sign as that of the solid particles in the fluid 56 is coated on the components, thereby creating a 57 repulsive force between the solid particles in the fluid 58 and the component surface [1][2][3][4][5][6]. This is a unique 59 and excellent method that takes advantage of the 60 intrinsic characteristics of the material and does not 61 consume energy to suppress deposition. 62The chemical solution deposition (CSD) method 63 considered in this study is a well-established practi-64 cal process to coat large parts [7][8][9][10][11]. In the CSD 65 method, a ceramic film is formed on a substrate by 66 first depositing a ceramic precursor solution on the 67 substrate surface and then applying heat treatment to 68 decompose the precursor. This process is advanta-69 geous in that it does not require special equipment 70 and is applicable to large parts with complex shapes. 71 However, films formed using CSD typically have a 72 characteristic microstructure with continuous pores 73 [22][23][24]. 74Many of the large parts that are considered in this 75 study are metallic. Therefore, accurate measurement 76 of the zeta potential of a film containing continuous 77 pores that is coated on a metal substrate is necessary. 78 Electrophoresis is also commonly used to evaluate 79 zeta potential, but this method involves the applica-80 tion of a high voltage to the electrolyte solution and is 81 therefore difficult to use in electrically conductive 82 substrate [13]. The streaming potential method [12] 83 can be used to measure the zeta potential of a film 84 coated on a metal substrate. In the streaming poten-85 tial method, an electrolyte solution is passed between 86 two specimens placed on either side of a narrow gap 87 and the resulting voltage or current is measured. A 88 voltage is not applied in this procedure, and thus, 89 evaluation of the zeta potential of a film on a metal 90 substrate should be possible. This method requires 91 the application of pressure to move the electrolyte 92 solution. As a result, the electrolyte solution may 93 penetrate the pores of the film, resulting in interac-94 tions between the electrolyte solution and the sub-95 strate that could affect the measured zeta potential. 96Very few reports discuss the zeta potential of a film 97 containing continuous pores that is coated on a metal 98 substrate by the use of the streaming potential 99 method to measure. Lorenzetti et al. [14] coated a 100 TiO 2 film with a thickness of 30 lm on a Ti metal 101 substrate via a hydrothermal method using a Ti deposition process. J Ceram Soc Jpn 124:448-454 609 [11] Brinker CJ, ...
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