Electrogenerated chemiluminescence biosensor for glucose based on poly(luminol–aniline) nanowires composite modified electrode

Li, Guixin; Lian, Jinlan; Zheng, Xusheng; Cao, Jun

doi:10.1016/j.bios.2010.07.003

Cited by 49 publications

(11 citation statements)

References 46 publications

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“…The enhanced ECL intensity has a linear relationship with the concentration of glucose in the range of 1.0 9 10 -4 to 1.0 9 10 -3 mol L -1 , and the detection limit for glucose is found to be 5.0 9 10 -5 mol L -1 (S/N = 3) [78]. Some studies reported the synthesis of poly(luminol-aniline) nanowires composite (PLANC) on the surface of graphite electrode by electro-oxidizing the mixture of luminol with aniline in the H 2 SO 4 acidic medium to improve the analytical performances of the ECL biosensor for glucose [79]. Based on the linear relationship between concentration of H 2 O 2 and the quenching of ECL in Ru(bpy) 3 2+ /TPA system, procedures for the indirect determination of glucose with a FIA system were developed with a detection limit of 1.0 lM [80].…”

Section: Life Sciences/biomedical Analysismentioning

confidence: 97%

Applications of Electrochemiluminescence

Parveen

Aslam

et al. 2013

SpringerBriefs in Molecular Science

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The development of electrochemiluminescence (ECL) applications is a growing field, having the potential advantages of ECL over conventional chemiluminescence. ECL has found various applications in immunoassays, DNA probe assays, and aptasensors by employing ECL-active species as labels on biological molecules. The recent use of ECL to detect many chemically, biochemically, clinically, and environmentally important analytes is reviewed.

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Section: Life Sciences/biomedical Analysismentioning

confidence: 97%

Applications of Electrochemiluminescence

Parveen

Aslam

et al. 2013

SpringerBriefs in Molecular Science

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“…A C C E P T E D M A N U S C R I P T [31] GCE/CNTs/Nafion 5 -80 2 7.4 [17] Au/sol-gel/AuNPs 1 -5000 0.2 7.5 [20] GCE/MWCNTs/polyNiTSPc/Nafion 1 -100 0.08 7.4 [16] SCPE/Fe 3 O 4 10 -10000 1 8.0 [32] GCE/Graphene/Nafion 2 -100 1 7.4 [51] GE/PLANC 0.1 -50 0.03 9.0 [35] GCE/collagen membrane 0.6 -3000 a 0.06 a 8.5 [52] GCE/polyamide membrane 1.5 -300 a 1.5 a 8.5 [52] GCE/sol-gel matrix 50 -10000 26 9.0 [53] CCE 10 -10000 8.16 8.5 [54] SP graphite electrode microarrays 3 -3000 3 nr [55] GCE/PDDA-CS 0.0005 -40 0.0001 7.5 [56] GCE/AuNPs-MWCNTs/CS 1 -1000…”

Section: Accepted Manuscriptmentioning

confidence: 98%

“…Various nano-structured materials such as CNTs film [17], CNTs paste [31] and Au-NPs self-assembled onto a silica sol-gel network [20], Fe 3 O 4 -NPs [32], Au-NPs and Pd-NPs decorated CNTs [13,30], graphene Pt nanoflower/graphene oxide [33], C 60 embedded in tetraoctylammonium bromide [34], poly(luminol-aniline) nanowires [35] and hollow gold nanospheres [36] have been applied for the fabrication of glucose biosensor based on the monitoring of ECL signal of luminol.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Improved electrogenerated chemiluminescence of luminol by cobalt nanoparticles decorated multi-walled carbon nanotubes

Haghighi

Tavakoli

Bozorgzadeh

2016

Journal of Electroanalytical Chemistry

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Multi-walled carbon nanotubes (MWCNTs) were decorated with cobalt nanoparticles (CoNPs) by a simple thermal decomposition method. The prepared nanohybrid material (nanoCoMWCNTs) was then cast on the surface of a glassy carbon electrode (GCE) as a novel electrocatalyst for the construction of a sensitive electrochemiluminescence (ECL) sensor. The fabricated sensor (GCE/nanoCo-MWCNTs/Nafion) showed excellent electrocatalytic activity toward luminol and H 2 O 2 oxidation reactions at neutral media. Under optimal experimental conditions, the ECL signal intensity of the sensor was linear with the concentration of luminol in the range between 80 nM and 140 µM (r = 0.9963) and also with the concentration of H 2 O 2 in the range between 1 nM and 240 µM (r = 0.9980). Detection limits (S/N = 3) for luminol and H 2 O 2 were 8.7 and 0.2 nM, respectively. The relative standard deviations (RSD) for repetitive  ACCEPTED MANUSCRIPT 2 measurements of 100 µM luminol (n =10) and 10 µM H 2 O 2 (n=11) were 1.6% and 2.0%, respectively. Also, the prepared sensor was further modified with glucose oxidase (GOx) to fabricate a glucose ECL based biosensor (GCE/nanoCo-MWCNTs/GOx/Nafion). The fabricated ECL biosensor exhibited excellent performance toward glucose detection in the concentration range between 0.5 and 600 µM with a satisfactory detection limit (50 nM) and reproducibility (2.3%).Electrogenerated chemiluminescence or electrochemiluminescence (ECL) is an attractive analytical tool with broad applications in different research areas. ECL is a hybrid technique which provides electrochemical and spectral information, simultaneously [1]. Simple and lowcost instrumental set up, excellent sensitivity and low background signal are the most important features of ECL [2,3]. A increased interest is observed for ECL investigations and this fact has been reflected in the number of reviews [4][5][6][7][8][9] which report the effectiveness of ECL detection method and its wide analytical applications.Luminol (2, 3-aminophthalhydrazide) is the most popular organic luminescent species which can be oxidized at the electrode surface. The subsequent chemical reaction between the oxidized luminol and H 2 O 2 (or O 2 ) produces ECL signal. Since the first report on the observation of ECL response for luminol at the electrode surface in alkaline solution [10], numerous attempts have been done to find effective approaches for the enhancement of ECL signal intensity of luminol in neutral medium [11][12][13][14]. It has been shown that the ECL reaction of luminol with oxygen or hydrogen peroxide is more efficient in alkaline medium through modification of the electrode surface with nano-materials [12,15].With the development of nanotechnology, various types of nano-structured materials with outstanding properties are being synthesized and applied for the construction of novel sensors and biosensors. Nano-structured materials provide higher effective surface area and higher catalytic activity in comparison with their respective bulk materials. The catalyti...

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“…Recently, the interest in practical electrochemiluminescence (ECL) glucose sensors has been centered on the efforts to find a breakthrough in the sensitivity and applications. In the glucose biosensors based on luminol ECL [2][3][4][5][6], hydrogen peroxide produced by enzymatic reaction of glucose oxidase (GOD) is used to enhance luminol ECL in the detection of glucose. The luminescence efficiency of luminol ECL is higher than those of other ECL reagents; however, the poor measurement stability caused by the alkaline media in luminol ECL is still a serious problem.…”

Section: Introductionmentioning

confidence: 99%

Electrochemiluminescence glucose biosensor based on glucose dehydrogenase functionalized Ru(bpy)3 2+ doped silica nanoparticles

Guo

Chen

2011

Sci. China Chem.

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A novel electrochemiluminescence (ECL) sensing approach was developed for glucose detection based on crosslinking Ru(bpy) 3 Cl 2 -doped silica nanoparticles (RuSiNPs) with glucose dehydrogenase on a glassy carbon electrode (GCE). Glutaraldehyde and aminopropyltrimethoxysilane were used as linking agents, and chitosan was used to immobilize the composites onto the GCE surface. The ECL sensor presented good characteristics in terms of stability and reproducibility. Under optimized conditions, the linear response of ECL intensity to glucose concentration was valid in the range of 0.2 to 20 mmol/L (R 2 = 0.9962). The application results indicated that the proposed approach is with great potential in the determination of glucose.

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Electrogenerated chemiluminescence biosensor for glucose based on poly(luminol–aniline) nanowires composite modified electrode

Cited by 49 publications

References 46 publications

Applications of Electrochemiluminescence

Applications of Electrochemiluminescence

Improved electrogenerated chemiluminescence of luminol by cobalt nanoparticles decorated multi-walled carbon nanotubes

Electrochemiluminescence glucose biosensor based on glucose dehydrogenase functionalized Ru(bpy)3 2+ doped silica nanoparticles

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